Immunocal the Only Proven Whey To Boost Glutathione - 25 years of Research, 80 International Patents Worldwide, Over 80,000 Clinical Studies

Dr. James Balch, distinguished co-author of best selling books, "Prescription for Natural Cures" and "Prescription for Nutritional Healing" with over 8,000,000 copies sold has this to say about Immunocal....

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Most Doctors agree that Aging and Disease are caused by Oxidative Stress and Free Radical damage.

Oxidative Stress and Free Radical Damage occurs in our bodies as a normal course of daily living. It comes from exercise, pollutants in the air, even the food we eat and drink. If left unchecked our bodies would deteriorate from the inside out.

The good news is that we were created with the ability to produce a molecule (found in every cell in our body) that is called GLUTATHIONE (GSH). Surprisingly, glutathione was discovered circa 1888 but not until the last 20 years have scientists really understood its importance. Scientists now refer to glutathione as The Master Antioxidant. Without GSH we literally cannot survive.

The key to understanding the importance of GSH is that many of the diseases we know of are associated with low levels of glutathione. Therefore, elevated levels of Glutathione fight against MS, Alzheimers, AIDS, Diabetes, Heart Disease, Cancer, Crohns Disease, Lung Disease, Parkinsons, Lupus and many more.

The production is dependent upon the availability of the amino acid Cysteine. After 25 years of research HMS 90 / Immunocal was the discovery of Gustavo Bounous, MD which is the Ideal Source of Cysteine. HMS 90 / Immunocal is an Undenatured Whey Protein Isolate that has 10 Method of Use Patents in 80 countries worldwide. This is a critical distinction when compared to any product that only have a composition patent.

Unfortunately, some misinformation also exists that can confuse the average person who is just trying to improve their health. Some companies try to sell glutathione pills that are just passed thruough your body as waste. They do nothing or at best, very little to increase glutathione serum levels.

Also, often touted to raise GSH levels is an anitoxidant drug called NAC which only has short term benefits and is sold without discussing the side effects.

The only proven safe and natural whey to improve your health is by providing your body with the precursor or building block Cysteine found in HMS 90 / Immunocal.

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Immunotec is a company that has been established on 2 decades of clinical research and was built upon its flagship product Immnunocal/HMS 90.

New and improved Immunocal Platinum adds a new dimension and choice for you and your health.

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World-class doctors, scientists and educators provide the genius and vision behind the growth and reputation of Immunotec.

Dr. Gustavo Bounous, MD - Director, Research & Development
Dr. Bounous discovered Immunocal/HMS 90. The studies he started in 1978 on the discovery and development of a dietary protein source from whey concentrate have become the standard by which all other whey products are measured.

* Honored as a Career Investigator of the Canadian Research Council
* Recipient of the Medal of Royal College of Physicians
* Lifetime member of the Research Council of Canada

Dr. Wulf Dröge, Ph.D. - Senior Vice-President, Research & Development
A world-renowned research scientist, Dr Dröge has devoted more than forty years to basic and clinical research that form the basis for the design of safe, effective new Immunotec products.

* Published over 260 times in peer-reviewed publications
* Postdoctoral fellowships at the Max Planck Institute and Harvard University
* Continues to write articles and teach at McGill University

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Some products on the market today promote themselves using the research of other companies. It is easy for a company to get a Composition Patent. Basically, submit your "recipe" for your product and you can claim that your product is patented. But what does that really mean to me and you?

Method of Use patents on the other hand, are Very Different. In order to get this type of patent you need to complete double blind studies (using your product), peer reviewed papers, needs to be renewed annually and on an on.

Immunocal has 10 Method of Use patents.

To see the U.S. and Canadian patents, click on the links below.

United States: 5,888,552, 5,451,412, 5,230,902, 5,456,924, 5,290,571, 5,846,939

Canada: 2,142,277,2,090,186, 1,333,471 1,338,682

Immunocal has been tested as part of ConsumerLab.com's Athletic Banned Substance Screening Program which screens for over 170 substances (including metabolites) based on the 2007 World Anti-Doping Code Prohibited List and has been certified free of any prohibited substances. The screening includes testing for stimulants, narcotics, anabolic agents, diuretics, masking agents and beta blockers based on the Olympic Movement Anti-Doping Code or the codes of other sports organizations. Click to view Immunocal on ConsumerLab.com's website.

For purposes of this testing, ConsumerLab.com acquired product through an independent representative, ensuring that product tested was randomly selected from a specific lot. Lot number for the testing was A3030731L, with an expiry date of 2009. To pass, a product must contain no confirmed Banned Substance at a "zero-tolerance level".

ConsumerLab.com reserves the right to disqualify a product at any time from passing its testing if it considers such product to present a safety risk or to provide misleading or inaccurate information. Athletes have long included Immunocal in their training regimens based on its scientific validation.

Studies such as that by Dr. Larry Lands on the "Effect of supplementation
with a cysteine donor on muscular performance" show that Immunocal can be an effective part of the athlete's nutritional supplementation.

President and Chief Executive Officer, Jim Northrop underlines that this latest substantiation of Immunocal's safety reinforces Immunotec's commitment to providing the public with the highest integrity nutritional supplementation available.

Immunocal has numerous North American and International patents, is listed in the Physicians' Desk Reference, the Pharmacist's Red Book and is approved for Medicare/Medicaid coverage in the U.S. Immunocal/HMS 90® has regulatory approval and a Natural Product Number from Health Canada as a natural source of the glutathione precursor cysteine for the maintenance of a strong immune system.

While some companies use an Antioxidant Drug called NAC to boost glutathione, Immunocal is as safe as mothers milk.

Natural Product Number Issuance by Health Canada of Immunocal/HMS 90

Immunotec received our Natural Product Number (NPN) from Health Canada for our Immunocal/HMS 90.

What does the issuance of the NPN mean? Basically it validates the efficacy, safety, and quality of the product by Health Canada and reassures the consumer about making an informed choice on the selection of the appropriate Natural Health Product.

Health Canada instituted the Natural Health Products Regulations, which was created to regulate the compliance, sale, and advertising of NHPs. The purpose of this regulation is to impose high standards and ensure that the Natural Health Products must be manufactured, packaged, and labelled in cGMP (current Good Manufacturing Practices) facilities.

How does Health Canada define Natural Health Products (NHPs)? They are classified as "vitamins & minerals, herbal remedies, homeopathic medicines, traditional medicines (such as Traditional Chinese Medicines), probiotics, as well as other products like amino acids".

Since the enactment of the Natural Health Products Regulation in 2004, Health Canada has received over 24,000 applications, of which only 4,000 NPNs have been issued.

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RAISING GLUTATHIONE USING CYSTEINE

Enhancement of Glutathione levels through cysteine supplementation has proven and important health benefits. But consumers have questions about the best available source of cysteine. Immunotec provides the answer.

IN SEARCH OF THE BEST STRATEGY FOR CYSTEINE SUPPLEMENTATION

By Dr. Wulf Dröge, Senior Vice-President, Research and Development

A series of clinical studies and complementary laboratory experiments has shown that aging is associated with a progressive decrease in plasma cysteine and intracellular glutathione concentrations. This decrease leads to (and can be viewed as a manifestation of) age-related oxidative stress. Cysteine and glutathione concentrations are particularly low during the night and early morning hours, i.e. during periods of starvation.

Several clinical studies have also shown that cysteine supplementation on top of the regular diet ameliorates several aging-related processes and improves amongst other parameters skeletal muscle functions and infl ammatory cytokine levels. Most of these studies have been performed with N-acetylcysteine (NAC). This was the best choice for this purpose because the free amino acid cysteine is not very stable and cysteine-rich proteins such as IMMUNOCAL® contain various different amino acids and would not have been helpful in studies designed to identify cysteine as the most important amino acid in this context.

The search for the best strategy to supply additional amounts of cysteine to the average consumer is now raising a very different and practical question. Not surprisingly the answer is different.

Let us compare NAC with IMMUNOCAL®.

NAC has some adverse effects which are not shared by IMMUNOCAL® and which render NAC unattractive as a source of cysteine over long periods of time. In addition, there are studies to suggest that dietary cysteine from any source is converted within the blood into its less accessible derivative cystine and within the liver into its breakdown product sulfate unless it is rapidly cleared from the blood by protein synthesis in skeletal muscle and other tissues. The undenatured whey protein IMMUNOCAL® provides all protein-forming amino acids and is known to stimulate rapid protein synthesis within less than 2 hours. This process allows the body to store cysteine until it is recovered by regulated protein breakdown during periods of starvation, i.e. during the night and early morning hours. IMMUNOCAL® is clearly superior to NAC in stimulating this process of cysteine storage.

Dr. Wulf Dröge, Ph.D. - A world-renowned research scientist, Dr. Dröge has devoted more than forty years to basic and clinical research that form the basis for the design of safe, effective new immunotec products. Published over 260 times in peer-reviewed publications Postdoctoral fellowships at the Max Planck Institute and Harvard University Professor, Faculty of biology, University of Heidelberg and Head of the department of Immunochem., German Cancer Research Center. He continues to write articles and teach at McGill University & Research Development

IMMUNOCAL®. Accept no substitutes. Immunotec®

CYSTEINE, N-ACETYLCYSTEINE (NAC), AND IMMUNOCAL®

By Dr. Jimmy Gutman, Medical Consultant Research over the past quarter century has shown that the limiting factor for our body's ability to make glutathione, is the availability of cysteine in our diet. There are several options, let's look at cysteine itself, N-acetylcysteine (NAC) and IMMUNOCAL®.

The amino acid cysteine can be found in supplement form in pills and powders. Unfortunately just eating cysteine has not proved to be an effective way to raise glutathione. Cysteine alone is quickly oxidized in the digestive system and does not make it to the cells in an appreciable quantity. Cysteine must be in a form that can survive the trip through the gut, into the bloodstream and across the cell membrane.

NAC is a form of cysteine that has been chemically modified to be able to make this long journey from your mouth to your cells. NAC is used as a drug to raise glutathione in critical medical situations such as acetaminophen overdose. It is also the drug most commonly used in research studies investigating
glutathione augmentation. NAC suffers from two drawbacks. It is effective in raising glutathione only for a short few hours, which is why doctors must give it to patients throughout the entire day. Individuals who take NAC pills experience a peak in glutathione and then levels may crash, occasionally below baseline values. The other complication of NAC is that side effects such as nausea, vomiting and diarrhea are common.

After years of investigation, Dr. Gustavo Bounous developed what we know as IMMUNOCAL®. This is a protein supplement that has the ability to deliver cysteine to our cells. It can be viewed as a "cysteine delivery vehicle". Being a complicated natural protein, the transformation of cysteine into glutathione starts quickly, but continues over many hours as our digestion and metabolism do their job. Side effects from IMMUNOCAL® are very rare.

It must be kept in mind that the amount of cysteine in IMMUNOCAL® is not as important as the form of ysteine. For example, if you were to boil IMMUNOCAL®, the amount of cysteine would remain the same, but the ability to raise glutathione would be destroyed, because the cysteine would no longer be in a deliverable form for the cell to properly utilize.

The advantages of IMMUNOCAL® over cysteine and NAC are clear once the physiology is understood. Glutathione molecule and structure

There is absolutely NO PRODUCT ON THE MARKET, that claims to raise Glutathione that can support its claims with their own research like Immunocal.

Cysteine-rich protein REVERSES weight loss in lung cancer patients receiving chemotherapy or radiotherapy.

Tozer RG, Tai P, Falconer W, Ducruet T, Karabadjian A, Bounous G, Molson JH, Dröge W.

Cysteine-Rich Protein Prevents Weight Loss in Lung Cancer Patients:
A Promising Intervention Study

MONTREAL , Jan. 17, 2008 /PRNewswire-FirstCall/ - Immunotec Inc. (TSX-V: IMM) announced today the successful completion of a multi-center randomized, double-blind clinical trial on cancer-related weight loss (cachexia) in lung cancer patients which was performed in collaboration with various Canadian clinical centers (x). The research concluded that patients treated with IMN 1207 showed significant increases in body weight (Tozer et al.Antioxidants & Redox Signaling (2008) 10:395-402). Immunotec also announced the initiation of a follow-up study to confirm the positive results.

The massive loss of body weight and muscle mass in advanced cancer patients is typically associated with psychological stress, financial burden and a decreased quality of life. Until now there have been no dietary interventions known to satisfactorily prevent this process.

Immunotec's new study included 66 patients with advanced lung cancer receiving state of the art chemotherapy or radiotherapy. The patients had already suffered significant involuntary weight-loss prior to treatment. During a six month treatment period the patients were given either casein, a protein supplement low in cysteine which is widely used in clinical nutrition ("placebo") or IMN 1207, a specially-prepared glutathione enhancing cysteine-rich whey protein isolate supplied by Immunotec Inc. The results showed that patients in the placebo group continued to lose weight whereas patients treated with IMN 1207 showed a significant increase in body weight. Incidentally, these patients also showed an increase in strength and quality of life parameters. This study showed for the first time that cancer-related weight loss (cachexia) can be prevented by a single source of protein. Dr. Gerald Batist, Chair, Department of Oncology, McGill University stated "Having been involved in the early mechanistic studies of the therapeutic use of whey proteins, I'm pleased to see this particular formulation being tested in the clinic. The data to date encourage additional and expanded clinical trials". Dr. Wulf Droge, Senior Vice-President Research & Development at Immunotec Inc. emphasized that the results of this first trial should be viewed with cautious optimism. A second trial has been initiated to confirm the results.

Among other questions, this clinical trial also addressed the controversy about antioxidant use in chemotherapy. Since radiotherapy and many types of chemotherapy work by raising levels of oxidative stress and free radical formation to destroy cancer cells, oncologists have voiced concern that treatment of the patient with antioxidants may "protect" the cancer from the toxic effects of the therapy. If this were the case, antioxidants could even be expected to shorten the life span of the patients. Immunotec's study now showed that this was clearly not the case with IMN 1207. Based on his earlier work at his laboratory at the National Cancer Research Center of Germany (DKFZ) in Heidelberg, Dr. Droge was reasonably confident that supplementation with a critical precursor of the major cellular antioxidant glutathione, would actually improve the condition of the patients, most probably by ameliorating adverse effects of these therapies on the patients' healthy tissues. The results of this new study suggest that this is true. The antioxidant glutathione is distinct from other antioxidants including the popular antioxidant vitamins A, C, and E which are widely used as nutritional supplements. Glutathione is involved in the removal of reactive oxygen species and other potential toxic compounds through special biochemical processes and can reach relatively high and beneficial concentrations in cells and tissues depending on the availability of its biosynthetic precursor cysteine.

About IMN 1207 from Immunotec Research (Immunocal plus)

IMN 1207 is a cysteine-rich protein. It is the research formulation of the undenatured whey protein Immunocal(R)/HMS 90(R), a dietary natural health supplement, developed and marketed worldwide by Immunotec during the past 12 years. Immunocal(R)/HMS 90 is a precursor of the major cellular antioxidant glutathione, an element important in maintaining a strong
immune system.

About Immunotec Inc.

Immunotec is engaged primarily in the development and marketing of natural health products, dietary supplements, food, vitamins and personal care products. Immunotec's products are distributed and sold in Canada and the United States through a network marketing system and in other countries through exclusive distributorship agreements. Immunotec's investment in this study is another manifestation of its ongoing commitment to research and development.

x Montreal General Hospital (McGill University teaching hospital) Montreal , Quebec , Canada

x Cross Cancer Institute, Alberta Cancer Board (University of Alberta affiliate) Edmonton , Alberta Canada

x Jewish General Hospital (McGill University teaching hospital) Montreal Quebec,Canada

x Juravinski Cancer Centre (McMaster University and Hamilton Health Sciences affiliate) Hamilton , Ontario,Canada .

x Allan Blair Cancer Centre (a division of Saskatchewan Cancer Foundation) Regina , Saskatchewan , Canada .

PMID: 18158761 [PubMed - in process]

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A New Outlook on Life's Health Challenges
Let's face it, most of us live a fast-paced lifestyle that is very demanding on our health. The habit of reacting only once the body breaks down is giving way to the realization that prevention can be the best medicine.

Glutathione is emerging as one of the keys to the health puzzle. It was the discovery of glutathione's importance in optimizing your body's first line of defense - your immune system - that led to the development of a whey product that raises intracellular glutathione.

Glutathione: The Next Household Word
You may or may not have heard of glutathione, even though over tens of thousands of medical articles have highlighted its importance. Optimizing glutathione levels will shortly join the list of factors known by everyone to have an impact on our health and well-being, along with vitamin supplementation and cholesterol regulation.

Glutathione is a small protein produced naturally in every cell of our body. It is made up of three protein building blocks, called amino acids. These are glutamic acid, cysteine and glycine. The cysteine amino acid contains a sulfur group responsible for the chemical properties of the whole glutathione protein.

Glutathione: An Essential Health AID
There are three major roles of glutathione in the body: Antioxidant, Immune booster, and Detoxifier. Even cells in the healthiest of individuals constantly need to replenish their glutathione supply.

The Master Antioxidant (AID)
Antioxidants participate directly in the destruction of reactive oxygen compounds called free radicals. These by-products of a cell's normal function can't be avoided, but exposure to ultraviolet radiation from the sun or other sources promotes their emergence. Free radicals have been linked to muscle fatigue during exercise and aging.

For this reason, the body is equipped with a variety of antioxidants. Vitamins C and E are natural antioxidants but do not occur naturally in the body. These and other antioxidants actually depend on glutathione to function properly, which is why glutathione is called "the Master Antioxidant".

Food For the Immune System (AID)
Glutathione helps build your immune system's resistance and improve your chances of staying healthy.

Lymphocytes are cells of your immune system. Glutathione is essential for lymphocytes to increase in number, produce antibodies, and function efficiently.

A Natural Detoxifier (AID)
Our food and water sources are becoming increasingly contaminated with chemicals, as is the air that we breathe. Supplemental detoxifiers such as glutathione help to counter the effects of the toxins we inhale and ingest.

By physically binding to toxic compounds in cells, glutathione helps make them soluble - and harmless. The body can then eliminate these disarmed toxins in the bile and urine.

Raise Glutathione Levels But How?
The fact is, you can't ingest glutathione to feed it to your cells. Glutathione must be manufactured within your cells. What you can do is help this natural process by giving your body the glutathione building blocks it needs. The limiting factor in your daily intake of building blocks is the amino acid cysteine.

Cysteine, traveling alone as an amino acid through our digestive system, is poorly absorbed and very little of it will actually make the trip from our mouths to our cells. Luckily, when cysteine molecules bind to each other to travel in pairs, they can survive this process. They do this by forming a bond between sulfur molecules. These bonded cysteine amino acids are then called 'cystine'. Although this sulfur bond is resistant to the digestive process, it is easily broken if submitted to heat or mechanical stress.

Immuncal's Unique Manufacturing Process
Before Dr. Bounous and his colleagues devised the technique used to produce Immunocal, the scientific community was unsuccessful at producing a supplement rich in active bonded cysteine.

Immunocal is a highly purified protein powder isolated from whey (milk serum). Immunocal's secret lies in its proprietary manufacturing process that guarantees:

*The most natural of products isolated in the most natural of conditions.
*A protein source that remains active, which is accomplished by maintaining the fragile, precious bond between cysteine amino acids.
*An even distribution of active protein throughout the product, for the same efficacy inevery serving.

Raise Glutathione Levels - Safely and Naturally
There are other synthetic ways in which glutathione levels may be raised. However, the high level of side effects limits their long-term use. In contrast, Immunocal is just as effective and has no known side effects when used as directed. It contains natural proteins isolated from milk, but a negligible amount of lactose; therefore, even lactose - intolerant individuals can use it safely.

Immunocal: Feeding Bonded Cysteine to Cells
Numerous clinical studies have been performed, using the highest standard of scientific design, to prove Immunocal's efficacy and reliability. In one such study, Immunocal was proven to raise glutathione levels by 35.5% in lymphocytes.

What's more, testimonial evidence from thousands of satisfied customers in a dozen countries confirms what science was able to prove: Immunocal works!

*The Effect of Supplementation with a Cysteine Donor on Muscular Performance
Published in the Journal of Applied Physiology, 87: 1381-1385, 1999
by LC Lands, MD, PhD, VL Grey, PhD, AA Smountas, BSc*
*Division of Respiratory Medicine, Department of Pediatrics, Department of
Biochemistry, McGill University Health Centre - Montreal Children's Hospital,
Montreal, Quebec, Canada

This study was conducted in healthy adults for 3 months using the highest standard of scientific design (peer-reviewed, double-blind, randomized, prospective and placebo-controlled study) to ensure validity of the results. Statistical calculations were performed to analyze the results.

Praise and Recognition From the Past and Present
Immunotec Research Ltd., is a research organization first and foremost and as such, is dedicated to marketing products that have received the highest approval from the scientific community. Immunocal is no exception.

Scientists have shown their support for Immunocal in many ways through the years, from its inception to its introduction to the North American market in 1996:

*Immunocal is patent-protected worldwide
*Immunocal is also listed in the U.S. Physicians' Desk Reference and the Pharmacist's Red Book
*Immunocal joins a select group of nutritional products qualifying for reimbursement coverage under Medicare/Medicaid in the United States

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