Modified osteo-odonto-keratoprosthesis (MOOKP)

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Modified osteo-odonto-keratoprosthesis-the innovative discovery!

In many cases of severe corneal damage, a OOKP may the best or only choice.

"A tooth for an eye makes the blind see!"

Patients with blindness due to severe chemical burns, trachoma, Stevens-Johnson syndrome, ocular cicatricial pemphigoid,multiple corneal graft failure etc require a keratoprosthesis or a replacement of their natural cornea. In many such cases a keratoplasty (replacement of cornea from a cadaver) will not work because of the high rate of rejection. The only suitable alternative is a keratoprosthesis. A modified Osteo-odonto-keratoprosthesis (OOKP) is the best choice in such cases.

For the OOKP, the patient's own canine tooth root is used to fashion the prosthesis. The modified proceedure is credited to Dr. Falcinelli, and is an improvement of the original procedure of his teacher, Dr. Strampelini.

The modified OOKP (MOOKP) is basically a 2-step procedure. The first stage involves removal of the patient's canine tooth, and it is designed to hold the lens. Next, the tooth is paced in a pocket, which is created under the skin of the normal eye. A small piece of mucous membrane is than removed from the inside of the cheek and attached to the sclera of the injured eye. Five-months later, the second stage of the operation is performed. By now, the tooth, which is covered by soft tissue is removed from the pocket under the normal eye and placed behind the mucous membrane of the damaged eye, such that only the lens protrudes out of the eye.

The cost of OOKP would be around £8-10,000

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  • Reply
    Snakara velayudhan Nandakumar Oct 2, 2009 @ 9:33 pm | delete
    Why dont we regrow our damaged teeth by similar procedure?
  • Reply
    Patti Sep 19, 2009 @ 3:24 am | delete
    It had been done in Singapore before.
  • Reply
    DMesser Sep 18, 2009 @ 7:15 am | delete
    Where can I find a more in depth description of how and why this works? The original document may be too in depth but I would like to understand the principles behind the procedure.
  • Reply
    Mohamed Jun 21, 2009 @ 12:27 am | delete
    I am asking about the centers arround the world where odonto keratoprosthesis surgery can be done.
  • Reply
    Christian Fau, MD, MSc Apr 4, 2009 @ 9:24 pm | delete
    The center MOOKP Prof. Dr. Giancarlo Falcinelli (Modified Osteo-Odonto-Keratoprosthesis), is located in the Service of Ophthalmology of the Clinical Hospital of the University of Chile. The center has a narrow relationship with the Foundation of OOKP of Roma, Italy.

    http://www.mookp.org

    The purpose is the decrease of the blindness of corneal cause in the country and in LatinAmerica.
    The technique of OOKP (Osteo-Odonto-Queratoprotesis) it was developed more than 35 years ago by the Dr. Benedetto Strampelli, later on the technique was perfected by means of modifications made by the Prof. Dr. GianCarlo Falcinelli, the technique that is recognized and accepted in the world, and that at the moment it is certified by means of a protocol Rome-Vienna published in the magazine it Horns in the year 2005.
  • Reply
    drwatson101 Feb 17, 2009 @ 9:54 pm | delete
    Now that is definitely a creative use of the reusing healthy parts of ones physical body to repair other damaged units.

    It is always reassuring to see how our bodies adapt and heal with a little prodding, or perhaps a lot in this case.

    In a related category here is a site on
    Ocular Nutrition

    Thanks Dr. Menon for explaining Dr Falcinelli's innovative work and the great images that help explain as well.
  • Reply
    Anup_Menon Aug 2, 2008 @ 9:15 am | delete
    A great innovative discovery indeed!
  • Reply
    gayathri Aug 1, 2008 @ 11:48 pm | delete
    iam very much impressed with this prosthesis...hats off to DR.FALCINELLI

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Anup_Menon

A surgeon by profession,  I try to bring you the latest advances, tips and cutting edge technology in medicine!

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