Benefits of CoEnzyme Q10

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Co Enzyme Q10 - Where was it discovered?

Karl August Folkers reported Co Enzyme Q10's structure while working at Merck. Merck is one of the largest pharmaceutical companies in the world. The Merck headquarters is located in Whitehouse Station, New Jersey, an unincorporated area in Readington Township. In 1972, Gian Paolo Littarru and Karl Folkers separately demonstrated a deficiency of CoQ10 in human heart disease

What is the role of Co Enzyme Q10 in the body?

HealthCoQ10 is found inside most cells. It works while the cell produces energy and acts while the cells transfer electrons throughout the energy chain. CoQ10 functions as an electron carrier since no other molecule can perform this function. Thus, CoQ10 functions in every cell of the body to synthesize energy. The antioxidant nature of CoQ10 derives from its energy carrier function. CoQ molecules will quite easily give up electrons and, thus, act as an antioxidant. CoQ10 protects not only fats, but also proteins from oxidation. In addition, the reduced form of CoQ effectively regenerates vitamin E. The circulating CoQ10 in LDL prevents oxidation of LDL, therefore, by providing its benefits in cardiovascular diseases.

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CoQ10 Maintains a Healthy Heart

Healthy HeartsCoenzyme Q10 helps to maintain a healthy cardiovascular system. Oxidation of the fat in the blood is thought to play a key role in the clogging of arteries, which is the underlying disorder leading to heart attack and ischemic strokes. A recent (2007) meta-analysis of the clinical trials of CoQ10 for hypertension reviewed all published trials of coenzyme Q10 for hypertension, and assessed overall efficacy, consistency of therapeutic action, and side-effect incidence. Meta-analysis was performed in 12 clinical trials (362 patients) comprising three randomized controlled trials, one crossover study, and eight open-label studies. The meta-analysis concluded that coenzyme Q10 has the potential in hypertensive patients to lower systolic blood pressure by up to 17 mm Hg and diastolic blood pressure by up to 10 mm Hg without significant side-effects.

CoQ10 For Migraines

HeadachesSupplementation of coenzyme Q10 has shown to help with migraines. In a trial of CoQ10, 61.3% of the patients achieved at least a 50% reduction in frequency of Migrains. CoQ10 has been used effectively in the management of migraines, especially in combination with a daily supplement of magnesium citrate 500 mg and riboflavin (vitamin B2) 400 mg. Although research and development of Migraine abortives has made great strides in recent years, work on preventives has been woefully lacking.

CoQ10 As a Supplement

CoQ10 Supplements

A successful use of CoQ10 was to use the use the supplement with soybean oil (lipid microspheres) which could be stabilised very effectively by lecithin and put in capsules.Although an almost negligible improvement of bioavailability was observed by Kommuru et al. with oil-based soft-gel capsules in a later study on dogs, the significantly increased bioavailability of CoQ10 was confirmed for several oil-based formulations in most other studies. Facilitating CoQ10 absorption by adding to water is a common strategy and is shown to be successful for Coenzyme Q10. The importance of how drugs are formulated for bioavailability is well known. In order to find a principle to boost the bioavailability of CoQ10 after oral administration, several new approaches have been taken and different formulations, and forms have been developed and tested on animals or humans.

CoQ10 Benefits

Healthy BenefitsCo Enzyme Q10 Helps to improve stamina and endurance, and can help maintain performance as well as assist recovery following exercise.
Women's Health: Women taking oral contraceptives have lower levels of CoEnzyme Q10 and Vitamin E, and could possibly benefit from supplementation. CoEnzyme Q10 is a powerful free radical scavenger that may assist in maintaining peripheral circulation and reduces oxidation of LDL (bad) cholesterol. If you are taking cholesterol lowering medication (statin) you might consider also taking CoEnzyme Q10. Cholesterol lowering medications can reduce the levels of CoEnzyme Q10 and supplementation is recommended to maintain energy levels.
CoEnzyme Q10 is a natural vitamin-like substance that is found in all body cells, particularly in the heart muscle. It is involved with the production of adenosine triphosphate (ATP), which is the basic energy unit of all cells, and declines as we age and with exercise. CoEnzyme Q10 helps provide stamina and endurance; assists maintenance of heart health - in particular heart muscle function and peripheral circulation; and assists with reducing the oxidation of LDL-cholesterol (the so called 'bad' cholesterol).

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