During the autumn of 2002, Beyonce Knowles was the featured vocalist on rapper Jay-Z's hit single, "'03 Bonnie & Clyde". In the spring of 2003, Beyonce Knowles remade a duet with the late Luther Vandross, "The Closer I Get to You", originally made famous by Roberta Flack and Donny Hathaway. In this version, the vocal parts are switched, with Vandross taking Flack's part and Knowles taking Hathaway's. The song was included on both her solo debut album and on Vandross's Dance with My Father album, and the two shared the Grammy for "Best R&B Performance by a Duo or Group with Vocals" that same year. Beyonce Knowles recently collaborated with her beau, Jay-Z, on his latest album, Kingdom Come, providing the vocals and the hook for the track entitled "Hollywood".

In 2003, Beyonce Knowles released her debut solo album, Dangerously in Love. The album entered the Billboard 200 at number one in its first week. The album has sold over four million copies in the US. When her single and album simultaneously topped the main singles chart in both the U.S. and the UK, Beyonce Knowles became the first act to achieve this feat since Men at Work in 1983, The Beatles, Simon and Garfunkel, and Rod Stewart in the 1960s and 1970s - thus becoming the first and so far the only female artist to do so. Beyonce Knowles was consequently one of the biggest-selling artists of 2003. Together with single and album sales they equal to a whopping thirty-three million in sales.

Towards the end of the summer, "Baby Boy", Dangerously in Love's second single, which featured dancehall artist Sean Paul, began to climb the charts. Afterwards Beyonce Knowles released her third solo single, "Me, Myself and I"; Dangerously in Love's fourth single, "Naughty Girl", came out in mid-2004.

At the 2004 Grammy Awards ceremony, Beyonce Knowles won a record-tying five Grammy Awards for her solo effort. Three other female artists hold this record: Lauryn Hill (1999), Alicia Keys (2002), and Norah Jones (2003). Beyonce Knowles also won a Brit Award in 2004 for "International Female Solo Artist" in the United Kingdom.

In December 2005, Beyonce Knowles released "Check on It", featuring rappers Slim Thug and (in the official remix) Bun B. The song was from the Destiny's Child's greatest hits compilation, #1's and the soundtrack to the 2006 film The Pink Panther and it was Beyonce Knowles' sixth top five hit and third number one in the U.S.

At the 2006 Grammy Awards, Beyonce Knowles won a Grammy in the category of "Best R&B Performance by a Duo or Group with Vocals" for the song "So Amazing", a duet with Stevie Wonder from the Luther Vandross tribute album So Amazing: An All-Star Tribute to Luther Vandross.

Beyonce Knowles' sophomore album B'Day was released worldwide on September 4, 2006 and on September 5, 2006 in the U.S. to coincide with the celebration of Beyonce Knowles's twenty-fifth birthday. In its first week, the album sold more than 541,000 copies in the U.S., immediately coming in at number one, making it her highest first-week sales as a solo artist. In the UK, it debuted at number three with sales of 35,000 copies, and has sold in excess of 300,000 copies, making the album Platinum. "Deja Vu", the album's first single, features Jay-Z. Also with the co-production by Rodney Jerkins. Currently, the album is certified 2x Platinum and has sold two million copies in the U.S. and more than three million copies worldwide.

The album's lead single "Deja Vu" became a top five hit in the United States and a number-one hit on the U.S. R&B chart and the UK chart, making it Beyonce Knowles's second UK number-one single, when it climbed twenty spots to take the top spot over Shakira featuring Wyclef Jean's "Hips Don't Lie" in the week of August 27, 2006.

The second single, "Ring the Alarm", was leaked to the Internet on August 8, 2006. The video for "Ring the Alarm" was released on August 16, 2006 on Yahoo and peaked at number one on the site's video chart. "Ring the Alarm" became Beyonce Knowles's highest-charting single debut, when it debuted at number twelve on the singles chart. However, it was her first single to miss the top ten in the U.S. Outside North America, "Irreplaceable" was released as the album's second international single in October 2006. "Irreplaceable" is her fourth number-one as solo artist on Billboard Hot 100 chart. It is Beyonce Knowles' eighth top ten hit in the U.S. as a solo artist and fourth number-one hit on the Billboard Hot R&B/Hip-Hop Songs. In December 2006, a Spanish-language version of "Irreplaceable", called "Imprescindible", was released. "Irreplaceable" is now in its fifth consecutive week at number one on the Billboard Hot 100.

Beyonce Knowles won her seventh MTV Video Music Award - "Best R&B Video" for "Check on It" - at the 2006 ceremony in August 31. Beyonce Knowles also performed her hit single "Ring the Alarm" at the awards ceremony. In September 2006, Beyonce Knowles won three awards at the UK's MOBO Awards ceremony. In November 2006, Beyonce Knowles took home an award for "World's Best-Selling R&B Artist" at the 2006 World Music Awards.

On December 6, the nominations for the 2007 Grammy Awards were announced, and Beyonce Knowles received five: "Best Female R&B Vocal Performance" for "Ring the Alarm", "Best R&B Song" for "Deja Vu", "Best Contemporary R&B Album" for B'Day, "Best Rap/Sung Collaboration" for "Deja Vu", and "Best Remixed Recording, Non-Classical" for "Deja Vu" (Freemasons Club Mix - No Rap) (remixed by Russell Small and James Wiltshire).

Beyonce Knowles has also confirmed rumors to Univision that she and Latin superstar Shakira will be releasing a Spanglish Latin pop song entitled "Beautiful Liar". It will be featured on the re-issue of B'Day, which will also include Spanish-language versions of "Deja Vu", "Irreplaceable", and "Ring the Alarm" and the T.I.-featured version of "Upgrade U".

Beyonce Knowles also has been hailed by Entertainment Weekly as the 7th Most Entertaining Person of the Year of 2006 and Beyonce Knowles was ranked the highest musician on the list.

Beyonce Knowles will release her third studio album in mid-2007.

Beyonce Knowles has been dating rapper Jay-Z since 2002. The couple has never publicly discussed their relationship, but has reportedly been together for almost four years. Beyonce Knowles has stated that she believes that not publicly discussing their relationship has helped them. Jay-Z has said in a People magazine article that "we don't play with our relationship".

There were various rumors that the couple were to wed in late November/early December 2006 in the Caribbean. The rumors proved to be false.

In 2001, Beyonce Knowles turned to acting, starring alongside actor Mekhi Phifer in the MTV made-for-television film Carmen: A Hip Hopera.

In the summer of 2002, Beyonce Knowles co-starred in the film Austin Powers in Goldmember, playing Foxxy Cleopatra opposite Mike Myers and Michael Caine. Beyonce Knowles also recorded the song "Work It Out" for the film's soundtrack. "Work It Out" was a top ten hit in the UK and a top forty hit in the Netherlands, Australia, and Ireland, despite being Beyonce Knowles' biggest commercial disappointment to date in the U.S., where radio stations barely played the song and the video received very minor exposure, playing only on digital video channels, MTV Jams, and VH1 Soul.

In 2003, Beyonce Knowles starred opposite Cuba Gooding, Jr. in the film The Fighting Temptations, and recorded a song for it called "Fighting Temptation", alongside female rappers Missy Elliott, MC Lyte, and Free. Unlike Beyonce Knowles' own singles, the song did not become a hit, although the film was a moderate success at the box office.

Beyonce Knowles co-starred in the film The Pink Panther, playing the role of Xania, an international pop singer, opposite Steve Martin, who plays Inspector Clouseau.

Beyonce Knowles's latest film work is Dreamgirls, the film adaptation of the hit 1981 Broadway musical about a 1960s singing group loosely based on Motown all-female group The Supremes, as the Diana Ross-based character Deena Jones. The film is scheduled for release on December 25, 2006. The film opened number three at the box office with an eight million dollar opening weekend. Beyonce Knowles was quoted to say this was her first real acting film.

Beyonce Knowles, music producer David Foster, and his daughter, Amy Foster Gillies, wrote Destiny's Child's single "Stand Up for Love" for World Children's Day, an event which takes place annually around the world on November 20 to raise awareness and funds for children's causes worldwide. Destiny's Child lent their voices and support as global ambassadors for the 2005 World Children's Day program.

Beyonce Knowles and Kelly Rowland, along with Mathew Knowles, Tina Knowles, and sister Solange Knowles recently announced the formation of the Survivor Foundation, a charitable entity set up for the purpose of providing transitional housing for 2005 Hurricane Katrina victims and storm evacuees in the Houston, Texas area. The Survivor Foundation extends the philanthropic mission of the "Knowles-Rowland Center For Youth", a multi-purpose community outreach facility in downtown Houston.

Animal rights organization People for the Ethical Treatment of Animals (PETA) have voiced concern over Beyonce Knowles wearing and using fur in her clothing line, House of Deréon. After winning an online eBay auction, offered by VH1 for the Save the Music Foundation, to dine with Knowles in June 2006, two PETA members confronted the singer at a restaurant in New York City about her use of fur. Beyonce Knowles did not respond, and the PETA members were escorted out. On August 25, 2006, PETA wrote a letter of concern to Beyonce Knowles about the treatment of baby alligators in a photoshoot. Beyonce Knowles spoke to Arena magazine about the photoshoot for "Ring the Alarm", where a baby alligator had its mouth taped shut. Beyonce Knowles told Arena, "There was a shot where I held an alligator. (It) had (its) mouth taped - that was my bright idea." Knowles added, "He was really cute, but since his mouth was taped, he didn't have any way to defend himself. He was upset, so he peed on me. That was an experience." The organization contacted a biologist, who wrote a letter to Beyonce Knowles. "As a specialist in reptile biology and welfare, I'm concerned about your posing with a terrified baby alligator for your new album cover." He added, "Humans and alligators are not natural bedfellows, and the two should not mix at events such as photo shoots. In my view, doing so is arguably abusive to an animal".

Dangerously in Love (2003)
Crazy In Love
Naughty Girl
Baby Boy (Feat. Sean Paul) (remix version)
Hip Hop Star (Feat. Big Boi & Sleepy Brown)
Be With You
Me, Myself And I
Yes
Signs (Ft Missy Elliott)
Speechless
That's How You Like It
The Closer I Get To You (Ft Luther Vandross)
Dangerously In Love 2
Beyonce Interlude
Gift From Virgo

B'day (2006)
Deja Vu
Get Me Bodied
Suga Mama
Upgrade U
Ring The Alarm
Kitty Kat
Freakum Dress
Green Light
Irreplacable
Resentment