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ACC: Rimonabant Therapy Fails to Demonstrate Atherosclerosis
http://www.medpagetoday.com Steven Nissen, M.D., of the Cleveland Clinic CHICAGO -- Reducing abdominal obesity with the investigational diet drug rimonabant had a beneficial effect on metabolic profile, but did not demonstrate a significant reduction in percent atheroma volume on intravascular ultrasound, researchers reported here.





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Acomplia tablets contain the active ingredient rimonabant, which is a type of medicine called a cannabinoid-1 receptor antagonist.
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Rimonabant (also known as SR141716, Acomplia, Bethin, Monaslim, Remonabent, Riobant, Slimona, Rimoslim, and Zimulti)Rimonabant is currently being sold in the United Kingdom by Sanofi-Aventis and in Denmark by Sanofi-Synthelabo under the trade name Acomplia (which is the name used in 18 countries, as of 2007). Bethin, Monaslim, Remonabent, Riobant, Slimona and Rimoslim are generic forms available in India. If approved in the United States, it is intended to be marketed under the name Zimulti. is an anorectic anti-obesity drug. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite.
Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. In Europe, it is indicated for use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m², or patients with a BMI greater than 27 kg/m² with associated risk factors, such as type 2 diabetes or dyslipidaemia. In the UK, it has been available since the end of July 2006. As of 2008, the drug was available in 56 countries.
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Latest Blog Posts On Acomplia Rimonabant
- Merck Cancels Obesity Drug Development
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- Emerging Opportunities with Cannabinoids within the Medical Industry
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