Jurassic Park for Real? - Cloning Extinct Animals

1 - I can do better 2 - Jury's out 3 - Pretty darn good 4 - Splendiferous 5 - Awesometastic by 21 people | Log in to rate

Ranked #487 in Animals, #11,409 overall

Cloning the Extinct Tasmanian Tiger

Geneticists have cloned sheep, horses, cats and dogs. The next step it seems is to bring back the dead. Scientists are currently working on resurrecting through cloning an animal extinct since 1936. The Australian Tasmanian tiger, or thylacine, was hunted to extinction 73 years ago, but now geneticists think they can bring back the fierce predator using DNA from stuffed museum specimens.

"Bringing back an extinct creature would unlock the door to progress.
Who knows what other 'impossible' things may be on the other side?" 


~Michael Archer 

Cloning Project Background 

The project is headed by evolutionary biologist Michael Archer, dean of science at the University of New South Wales in Australia. In collaboration with colleagues at Australian universities and U.S. genetics labs, Archer hoped to bring this carnivourous marsupial back from extinction using DNA from an infant female preserved in alcohol since 1866.

Part of the difficulty lies in restoring the degraded DNA, in fact Archer's first team failed to extract quality DNA from the infant female and the project was scrapped in February 2005. But with a new team, new technology and a new strategy to recover genes from the bones and teeth of thylacines in museum specimens the project was revived again in October 2005.

If Archer's new team can figure out how to restore degraded DNA there is a chance the Tasmanian tiger could live again. What's next...the Woolly Mammoth? Actually that's not so far fetched...in fact there are projects underway to clone the mammoth as well as the Spanish bucardo goat.

How to Clone an Extinct Animal 

The basic steps to clone an animal are in theory pretty straight forward. Here are the six steps to creating a clone.
  1. Obtain Sample DNA:
    Find cells from the animal's tissue, bones, teeth, hair, etc.. Then extract the DNA from the cell's nucleus.
  2. Rebuild Genome:
    Reassemble the DNA of the extinct animal using the genome of a related living animal as a guide. In the tiger's case that is the Tasmanian devil.
  3. Swap DNA:
    Remove the ovarian eggs of the related animal and replace their nuclei with the restored genetic material from the extinct animal.
  4. Zap the Eggs:
    Fuse the nuclei with the eggs and trigger cell devision by shocking them with electric current or treating them with chemicals.
  5. Implant the Embryos:
    When the embyos have grown to 200 cells in size transfer them into the womb of the related animal for gestation.
  6. Delivery:
    The surrogate mother gives birth. The extinct species is reborn once again. It is scientists hope that the necessary survival skills will be coded into its genes.

Further Reading About the Tasmanian Tiger 

Tasmanian Tiger: The Tragic Tale of How the World Lost Its Most Mysterious Predator

Avg. Customer Rating: Amazon Rating

Amazon Price: $17.00 (as of 07/10/2009) Buy Now

Carnivorous Nights: On the Trail of the Tasmanian Tiger

Avg. Customer Rating: Amazon Rating

Amazon Price: $11.66 (as of 07/10/2009) Buy Now

The Last Tasmanian Tiger: The History and Extinction of the Thylacine

Avg. Customer Rating: Amazon Rating

Amazon Price: $22.49 (as of 07/10/2009) Buy Now

Woolly Mammoth: Back Again? 

Jarkov mammoth may be the key

In 1999, French polar explorer Bernard Buigues and mammoth experts Dick Mol and Larry Agenbroad unearthed a 23,000 pound block of permafrost containing the remains of a woolly mammoth near the Bolchaya Balakhnya River in Siberia.

Scientists were hopeful that the block of frozen earth would yield an intact mammoth carcass. The possibility led a number of genetic research facilities around the world to propose extracting DNA from the soft tissues of the extinct creature with the goal of cloning it back to life.

Unfortunately for those scientists interested in cloning the mammoth there was very little soft tissue and bone remaining. As in the case of the Tasmanian tiger there was just too little quality DNA to give cloning much of a chance.

But if scientists can discover a technique to restore degraded DNA the first major hurdle in cloning the mammoth will be overcome. That would just leave several other unknown factors including the gestation period of the mammoth. Will it match that of the Asian elephant, the mammoth's closest living relative? Not to mention there is a bit of a size difference between the woolly mammoth and the Asian elephant; what kind of problems will this cause for the surrogate mother?

All in all the odds are currently stacked against a successful clone, but with the ever expanding developments in genetics some day in the next 20-30 years there might just be woolly mammoth rides at your local zoo.

Woolly Mammoth Fact and Fiction 

More info on the woolly mammoth for your reading pleasure

Wild and Woolly Mammoths: Revised Edition (Trophy Picture Books)

Avg. Customer Rating: Amazon Rating

Amazon Price: $7.99 (as of 07/10/2009) Buy Now

Uncovering the Mysterious Woolly Mammoth

Avg. Customer Rating: Amazon Rating

Amazon Price: $10.87 (as of 07/10/2009) Buy Now

Woolly Mammoth (Pebble Plus: Dinosaurs and Prehistoric Animals)

Avg. Customer Rating: Amazon Rating

Amazon Price: $6.95 (as of 07/10/2009) Buy Now

What should we do about cloning? 

With each breakthrough in cloning research comes increased controversy. Should we be messing with nature? On one hand there may be a great number of discoveries that lead to better health or the preservation of endangered species, on the other hand there is a great moral dilemma involved when anyone mentions human cloning.

Loading poll. Please Wait...

Join the Cloning Debate 

Let the battle begin!

Since I've created this little page on cloning extinct animals I've had some comments from several people voicing their opinion on the merits or morals of cloning. And the above poll results show that not everyone is very keen on the idea of cloning especially when it involves human cloning.

So let's start a little debate so all voices can be heard. Is cloning the future and will it lead to many improvements in life? Or, is cloning something better left alone, something that may lead to the end of humans on earth?

How do you feel about cloning?

Loading Fetching blurbs now... please stand by

Cloning is the future deal with it!

The_Goblins_Den says:

Like it or not, I believe cloning will become an important part of our future society. It's probably not a good a idea to go and resurrect every animal from Earth's past...but if it can be done, you can bet someone will do it.

Rylan says:

Cloning could save human and animal lives alike. I think it along with stem cell research is perfectly fine.

the FUTURE says:

Cloning is a necessary thing the humans will have to prepare for. It could save the food supply for the future, provide organs to those who need it. It coud also be used to save an extinct species if it is perfected enough- like to save dinosaurs, mammoths or dragons- lol

Human Being says:

Those who desire to retard and hinder our most productive natural resource, the thinking human mind, are fools. Science will take us wherever we have the courage to follow it. Critics who lash out at science while using the Internet to do so are just sad . . . and funny. But mostly sad.

There should be no artificial limit placed on knowledge, only a natural limit.

NAtional Geo reader says:

WOw, to think one day the zoos would have wooly mammoth rides and sabbertooth tiger exibits is like my birthday wish came true. Now all the kids of the future might still see a polar bear or might even see something we never got to see like a dino.

Cloning is an unnatural abomination!

Science Hater says:

Cloning's wrong and god said in the bible that it ain't easy to clone no mammel and it sure ain't wright (Zachariah 7:32). I believe in jesus and that makes me distrust science cause jesus wasn't no scientist.

Also I live in a mobile home community, wear sleeveless t-shirts, and engage in the recreational usage of methamphetamines - so I don't know if that skews my perspective a bit or not. I do think I'm fairly representational of the typical anti-cloning proponent.

lesily says:

only god can create pefectly

Ariel linton says:

if every one in an area has the same genetic make up then a single disease could wipe out a huge amount of the population

Ariel linton says:

Cloning is wrong it is not our job to play God. Under developed kideys large tounges and squished faces are side affects of clones. Clones suffer if we make mistakes. STOP THE CLONING!!!!

Colton says:

Cloning Human beings is extremely pointless. I really dont see why we need to do it! cloning organs is fine, but not cloning humans to harvest their organs!!

 
1 of 7 pages
 

More Info on Woolly Mammoth and Thylacine Cloning 

Tasmanian Tigers and Woolly Mammoths galore!

Tasmanian Tiger Cloning Breakthrough
An article from the Australian Museum Online written in 2002 about Micheal Archer's Tasmanian Tiger cloning project.
Tasmanian Tiger Sightings
Just like stories of the Loch Ness monster or Big Foot, the thought to be extinct Tasmanian tiger enjoys similar notoriety in Australia. Here are several articles of Tasmanian tiger sightings, as well as more articles on the cloning efforts.
A Natural History of the Tasmanian Tiger
The online Thylacine Museum, an educational guide to the thylacine, or Tasmanian tiger. Tons of information covering virtually all aspects of the natural history of this unique Australian marsupial. A very comprehensive resource for those interested in the Tasmanian tiger.
Will the Mammoth Walk Again?
A Discovery Channel article about the discovery of the Jarkov mammoth and attempts to clone it.
Mammoth Cloning
An article stating some background on the woolly mammoth as well as the difficulties involved with cloning one.

Cloning Books and Resources 

More information for your cloning research

If you are interested in learning more about cloning, genetics and DNA analysis these fine books and laboratory manuals are a good place to start.

Molecular Cloning: A Laboratory Manual (3-Volume Set)

Avg. Customer Rating: Amazon Rating

Amazon Price: $233.10 (as of 07/10/2009) Buy Now

Gene Cloning and DNA Analysis: An Introduction

Avg. Customer Rating: Amazon Rating

Amazon Price: $58.77 (as of 07/10/2009) Buy Now

Condensed Protocols from Molecular Cloning: A Laboratory Manual

Avg. Customer Rating: Amazon Rating

Amazon Price: $89.10 (as of 07/10/2009) Buy Now

New Scientific American 

Current news in the science world

Birth Defect Study Casts Doubt on Phthalate Fears
Hypospadias, one of the most common birth defects among baby boys, apparently is not increasing in t...
El Nino Has Arrived
[Below is the original script. But a few changes may have been made during the recording of this aud...
Pride: Deadly Sin or Social Lubricant?
Think back to the last time that you beat a friend at a card game or outdid your previous record in...

What Bloggers are Saying About Cloning 

more fuel for the cloning controversy

The Benefits of Human Cloning | Raitucarp Magazine
Human cloning is the creation of a being, tissue or a cell that is genetically identical to a human. For ethical reasons progress on human cloning has been.
How do you feel about harvesting brain cells from a cloned ...
For the first time since Hwang Woo-Suk's cloned stem cells were revealed as fakes, human cloning ? for medical purposes, or even for reproduction ? appears to be a realistic possibility. ?We show for the first time that the same genes ...
Chief of Human Genome Project Tapped by Obama to Lead NIH
He has also voiced support for "therapeutic human cloning" or somatic cell nuclear transfer (SCNT), whereby the nucleus of a human egg is replaced with the DNA of an individual, resulting in the creation of a clone embryo of that ...

A Lens of the Day Selection 

9/28/06

A Thank you to the fine people of Squidoo for choosing this lens as Lens of the Day on September 28th 2006. And to the many readers who have graced this lens with their curiosity - may you all be cloned and visit again, and again.

Reader Feedback 

If you like this lens please don't forget to add this page to
del.icio.us , Digg , or Stumble Upon!


susannaduffy wrote...

I love this lens! I had to come back for another look

ReplyPosted April 05, 2009

AlishaV wrote...

Great lens! I've been interested in cloning ever since I realized that we are losing species of animals and plants every single day and without cloning, those wonderful species would be gone forever.

ReplyPosted January 27, 2009

susannaduffy wrote...

Excellent lens! Informative and thought provoking on a sensitive topic. Five high stars of course and linked as featured lens, as well as lensrolled, to my thylacine (tasmanian-tiger)

ReplyPosted December 09, 2008

Pantherart wrote...

Great lens, but no on the cloning, 5 stars

ReplyPosted November 29, 2008

Margaret_Schaut wrote...

I'm featuring your page on Squidoo-It-All! Great page!

ReplyPosted October 19, 2007

 
1 of 3 pages