Cushings disease is a glandular disorder caused by excessive corticosteroids. The process of the production of these corticosteroids is such that:

* The pituitary gland produces a hormone called ACTH
* The ACTH stimulates the adrenalin glands
* The adrenalin gland produces corticosteroids
* A more than required amount of corticosteroid can cause Cushings disease, so it is also called hyperadrenocorticism (hyper-adreno-corticism).

The overproduction of corticosteroids which causes Cushing's disease can occur due to two types of conditions. In 85% of the cases, the excessive production of ACTH is caused by a tumor in the pituitary gland that produces high levels of ACTH. This causes the adrenalin glands to make more than required levels of corticosteroids.

Hyperadrenocorticism in a dog can also be caused by a corticosteroid-producing tumor in one or both of the adrenalin glands.

Cushing's disease can also be caused by large doses of synthetic corticosteroids. These steroids may be administered for treating another ailment but in turn produce a side effect that results in Cushing's disease.

Cushing's disease generally occurs in dogs that are 5 years or older. It is more common in female dogs than in male dogs. Some breeds like Terriers, Poodles, and Dachshunds are more prone to Cushing's disease for some inexplicable reason.

Cushing's disease affects the overall health of the dog, since corticosteroids play an important role in a large number of body functions. Some of the symptoms of the disease are:

* A gradual but definite weakening of the ligaments
* Weight gain and a potbelly
* Degeneration of the skin leading to rashes and lumps
* Hair loss
* An increase in appetite
* High levels of liquid intake
* Higher frequency of urination
* A gradual degeneration of the nervous system

A series of tests need to be conducted to confirm the presence of Cushing's disease in dogs. Samples of blood and diluted urine are analyzed to give a preliminary indication. If the disease is suspected, further laboratory tests are performed that can be fairly accurate in diagnosis and can even direct the physician to the root of the problem.

Other endocrinal disorders like diabetes or inflammation of the pancreas tend to appear along with Cushing's disease. These ailments add to the suffering of the dog and unfortunately reduce the chances of survival.

Learn more at the Natural Pet Health Blog

Function and definition of the adrenal glands

The adrenal glands are two, small bean-shaped structures situated above each of your pet's two kidneys. They consist of two separate regions: an inner adrenal medulla surrounded by an outer adrenal cortex.

The adrenal glands release a wide variety of hormones. The medulla is responsible for producing epinephrine and norepinephrine (adrenaline). These hormones control the body's reaction to Stress and affect blood pressure and heart rate. The adrenal cortex produces hormones such as cortisone and aldosterone which are necessary for balancing fluid and electrolytes (salt) in the body as well as regulating the use of dietary protein, fats and carbohydrates and controlling Inflammation.

What are the symptoms of Cushing's Disease?

High levels of corticosteroids in the body can cause a number of health problems in pets including:

• Increased thirst/drinking and urination


• Increased appetite


• Panting


• High blood pressure


• Loss of hair


• Calcified lumps in the skin


• Thinning skin and susceptibility to infections

Over time, if not well-controlled, Cushing%uFFFDs can increase your pet's risk of other conditions including Diabetes, weakening of the heart and Nervous system disease.

What are the main causes of Cushing's in pets?

There are a couple of possible causes for Cushing's in pets. The first is that your pet may be taking in excess corticosteroids in the form of medications such as Prednisone. If your pet is not taking a drug like Prednisone and has been diagnosed with Cushing's, it is probably due to a tumor (usually benign) on either of the adrenal glands themselves or on the pituitary gland.

How can Herbal Remedies and dietary supplements help?

Though Natural Remedies will not cure Cushing's, many Herbs can safely and effectively support your pet's general health and help to reduce the symptoms of Cushing's disease.

A holistic approach to your pet's condition is the best approach: see below for dietary measures that can help your pet's general health.

What are Cushex Drops?

PetAlive Cushex Drops contain a blend of both herbal and homeopathic ingredients specially selected to treat Cushing's in pets. Each ingredient of this Natural Remedy has a specific role to play in normalizing adrenal function, balancing corticosteroid levels or reducing the troublesome symptoms of this condition.

Cushex Drops are easy to administer and the dosage can be adjusted to suit pets of all sizes.

Use PetAlive Cushex Drops To:

• Support the health of your pet's adrenal glands and encourage normal functioning


• Help reduce circulating levels of corticosteroids


• Encourage health of coat and prevent Hair loss


• Balance blood pressure and Blood Sugar Levels


• Reduce excessive thirst and urination


• Promote optimal strength and health of the skin


• Improve Digestive Functioning

How long until I see results?

Degree and speed of improvement differs from animal to animal, depending on many factors. With regular use, you should begin to notice a general improvement in health within 3 - 6 weeks.

How long does one bottle last?

One 50 ml bottle of Cushex Drops will last for 15 - 60 days, depending on the size and needs of your pet.

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