Bio-Synthesis Inc. the major supplier Custom DNA Synthesis
Since 1984, Bio-Synthesis, the first company to provide commercial custom DNA synthesis, has remained a major force in advancing biotechnology research both as leading supplier and developer of new technologies for unmodified DNA synthesis, custom DNA modifications, antisense oligos and DNA chimera. Biochemical researchers choose BSI as their major supplier for oligonucleotide synthesis because of our core values: QUALITY, SPEED and HIGH THROUGHPUT capabilities. Quality is not just a goal, it is a GUARANTEE. Every custom DNA synthesized must pass strict quality control guidelines before delivered to our customers. In addition to high quality production, speed of our custom DNA has improved to next day delivery in most cases. Through improvement from traditional chemistry to development of advanced state-of-the-art proprietary instrumentations, BSI has achieved the goal of providing the most economical, high throughput, quality custom DNA synthesis.
As always, every custom DNA synthesis is:
* Deprotected, desalted, lyophilized, Ready-2-Use
* Quantitated 2x by UV spectrophotometry to provide an accurate measure of yield
* Quality checked by MALDI-TOF mass spectrometry, purity check by HPLC and/or PAGE
* Custom preparative and analytical services (optional)
* Quality Assurance document including: yields, TM, MW, ug/OD and more...
* Fast delivery with high throughput capacity
Service:
Unmodified DNA Synthesis
We offered several scales of custom unmodified DNA synthesis at very competitive price. From small research custom DNA synthesis scale to large production of ASR and GMP DNA oligomers. We offer our client with one-stop solution for their custom DNA synthesis needs. See more...
Custom DNA Arrays/Libraries Oligo Synthesis
High-throughput custom DNA can be provided in 96 or 384 well plates. You can even request the plate type required for your system. Options for oligos in solution include equimolar concentration, forward and reverse primer in the same well, dilution in buffer or water, and equal or variable volume. Options for lyophilized oligos in plates includes equal nmole amounts or µg amount. See more...
DNA Modifications
BIO-SYNTHESIS offers thousand of custom DNA modifications to meet our clients needs. Modification such as DNA methylation, DNA base modification, backbone modification, and many others. See more...
Labeled DNA Probes
BSI's labeled DNA probes are routinely manufactured in 200 nmole or 1 umole scale. These fluorophore can be labeled at 5', 3' and internal position of an oligonucleotide. See more...
Antisense Oligos
Antisense oligos have been powerful tools to halt biological events, such as transcription, translation or splicing. At BSI, we offer hybrid synthesis of RNA-DNA with mix backbone linkages. See more...
Peptide Nucleic Acid (PNA) Sythesis
Synthesis of conjugated PNA offers researchers with a powerful tool for diagnostic as well as for pharmaceutical applications such as antisense therapy, cellular delivery, drug delivery. See more...
DNA Chimera
Synthesis of chimeric DNA, chimeric DNA/RNA, chimeric DNA and peptide provides companies and researchers with a powerful tool for pharmaceutical applications. BSI offers PNA/DNA chimera synthesis at competitive prices and quick delivery. See more...
Analyte Specific Reagent (ASR oligos)
Bio-Synthesis Inc. is registered with the U.S. Food and Drug Administration as a Medical Device Class 1 manufacturer for Analyte Specific Reagent (ASR) products, which includes custom nucleic acid sequences for: in vitro diagnostic manufacturers, clinical laboratories or organizations that use the reagent to make tests for purposes other than providing diagnostic information to patients and practitioners. Note: According to 21CFR809.30 (d), Class I ASRs must be labeled as: "Analyte Specific Reagent. Analytical and performance characteristics are not established."
Bio-Synthesis's ASR products (GMP Oligos) are manufactured under good manufacturing practices (cGMP) in compliance with FDA regulations 21CFR864.4020 and 21CFR820.
As always, every custom DNA synthesis is:
* Deprotected, desalted, lyophilized, Ready-2-Use
* Quantitated 2x by UV spectrophotometry to provide an accurate measure of yield
* Quality checked by MALDI-TOF mass spectrometry, purity check by HPLC and/or PAGE
* Custom preparative and analytical services (optional)
* Quality Assurance document including: yields, TM, MW, ug/OD and more...
* Fast delivery with high throughput capacity
Service:
Unmodified DNA Synthesis
We offered several scales of custom unmodified DNA synthesis at very competitive price. From small research custom DNA synthesis scale to large production of ASR and GMP DNA oligomers. We offer our client with one-stop solution for their custom DNA synthesis needs. See more...
Custom DNA Arrays/Libraries Oligo Synthesis
High-throughput custom DNA can be provided in 96 or 384 well plates. You can even request the plate type required for your system. Options for oligos in solution include equimolar concentration, forward and reverse primer in the same well, dilution in buffer or water, and equal or variable volume. Options for lyophilized oligos in plates includes equal nmole amounts or µg amount. See more...
DNA Modifications
BIO-SYNTHESIS offers thousand of custom DNA modifications to meet our clients needs. Modification such as DNA methylation, DNA base modification, backbone modification, and many others. See more...
Labeled DNA Probes
BSI's labeled DNA probes are routinely manufactured in 200 nmole or 1 umole scale. These fluorophore can be labeled at 5', 3' and internal position of an oligonucleotide. See more...
Antisense Oligos
Antisense oligos have been powerful tools to halt biological events, such as transcription, translation or splicing. At BSI, we offer hybrid synthesis of RNA-DNA with mix backbone linkages. See more...
Peptide Nucleic Acid (PNA) Sythesis
Synthesis of conjugated PNA offers researchers with a powerful tool for diagnostic as well as for pharmaceutical applications such as antisense therapy, cellular delivery, drug delivery. See more...
DNA Chimera
Synthesis of chimeric DNA, chimeric DNA/RNA, chimeric DNA and peptide provides companies and researchers with a powerful tool for pharmaceutical applications. BSI offers PNA/DNA chimera synthesis at competitive prices and quick delivery. See more...
Analyte Specific Reagent (ASR oligos)
Bio-Synthesis Inc. is registered with the U.S. Food and Drug Administration as a Medical Device Class 1 manufacturer for Analyte Specific Reagent (ASR) products, which includes custom nucleic acid sequences for: in vitro diagnostic manufacturers, clinical laboratories or organizations that use the reagent to make tests for purposes other than providing diagnostic information to patients and practitioners. Note: According to 21CFR809.30 (d), Class I ASRs must be labeled as: "Analyte Specific Reagent. Analytical and performance characteristics are not established."
Bio-Synthesis's ASR products (GMP Oligos) are manufactured under good manufacturing practices (cGMP) in compliance with FDA regulations 21CFR864.4020 and 21CFR820.
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About BSI
"The use of state-of-the art technology has allowed Bio-Synthesis, Inc. to rapidly gain recognition for its manufacturing quality & dependability of delivery."
Founded in 1984, Bio-Synthesis, Inc. was first known as OCS Laboratories. It was the first producer of commercially available synthetic DNA and, in 1985, became a producer of synthetic peptides. In 1989, OCS incorporated as Bio-Synthesis, Inc. and moved its laboratories to Lewisville, Texas. Today, BSI occupies 10,000 square feet of modern laboratory space (completed in 1995) located 20 miles from downtown Dallas and 10 miles from D/FW airport. Among the surrounding academic institutions are: University of Texas Southwestern Medical School (12 miles), University of North Texas (10 miles), and University of North Texas Health Science Center (25 miles). These universities provide excellent library resources. Since its inception, BSI has steadily expanded its product lines and services to meet the growing needs of the molecular biology community. It has maintained its position as an aggressive, innovative company in a highly competitive marketplace without sacrificing quality. In the beginning, our primary emphasis was on synthesizing high quality DNA primers and linkers, which were the initial uses of oligos. Today, newer technologies, such as gene construction, PCR, mutagenesis, combinatorial libraries, dye/adduct labeling, DNA microarrays, peptide-nucleic acid chimeras, etc. have challenged the molecular biology field. In response, BSI has branched into several related areas including DNA paternity testing, DNA HLA typing, PNA synthesis, genomic sequencing, fluorescence-based genotyping, custom organic synthesis and other molecular biology based applications.
The Research and Development Division comprises a number of Ph.D. and M.D. professionals with backgrounds in molecular biology, immunology, nucleic acids, peptide synthesis, general organic chemistry, and automated amino acid sequencing. The Molecular Biology Division is set up to handle most modern experimental procedures; the Immunology Division specializes in immunodiagnostic-based reagents.
Not only has BSI continued to provide quality DNA products and services for the research community, but it has also become a world leader in providing custom peptide products and services. Using state-of-the-art solid phase peptide chemistries, BSI provides high quality custom peptides, performs carrier conjugations, antipeptide antibody production, antigenic peptide design, synthesis of long and/or modified peptides, MALDI TOF analysis, contract research, consultation services and more.
Biomedical researchers worldwide in universities, biotech companies, private clinics, and government agencies use products from Bio-Synthesis, Inc. in studies ranging from PCR diagnostics to cancer research and the Human Genome Project. Contact us to discover how BSI can customize products/services to suit your research requirements.
For more detail please visit our About Us
Please Contact Us :
Address: 612 E. Main street
City: Lewisville
State: Texas
Country: USA
Postal Code: 75057
Phone Number: 972-420-8505
Founded in 1984, Bio-Synthesis, Inc. was first known as OCS Laboratories. It was the first producer of commercially available synthetic DNA and, in 1985, became a producer of synthetic peptides. In 1989, OCS incorporated as Bio-Synthesis, Inc. and moved its laboratories to Lewisville, Texas. Today, BSI occupies 10,000 square feet of modern laboratory space (completed in 1995) located 20 miles from downtown Dallas and 10 miles from D/FW airport. Among the surrounding academic institutions are: University of Texas Southwestern Medical School (12 miles), University of North Texas (10 miles), and University of North Texas Health Science Center (25 miles). These universities provide excellent library resources. Since its inception, BSI has steadily expanded its product lines and services to meet the growing needs of the molecular biology community. It has maintained its position as an aggressive, innovative company in a highly competitive marketplace without sacrificing quality. In the beginning, our primary emphasis was on synthesizing high quality DNA primers and linkers, which were the initial uses of oligos. Today, newer technologies, such as gene construction, PCR, mutagenesis, combinatorial libraries, dye/adduct labeling, DNA microarrays, peptide-nucleic acid chimeras, etc. have challenged the molecular biology field. In response, BSI has branched into several related areas including DNA paternity testing, DNA HLA typing, PNA synthesis, genomic sequencing, fluorescence-based genotyping, custom organic synthesis and other molecular biology based applications.
The Research and Development Division comprises a number of Ph.D. and M.D. professionals with backgrounds in molecular biology, immunology, nucleic acids, peptide synthesis, general organic chemistry, and automated amino acid sequencing. The Molecular Biology Division is set up to handle most modern experimental procedures; the Immunology Division specializes in immunodiagnostic-based reagents.
Not only has BSI continued to provide quality DNA products and services for the research community, but it has also become a world leader in providing custom peptide products and services. Using state-of-the-art solid phase peptide chemistries, BSI provides high quality custom peptides, performs carrier conjugations, antipeptide antibody production, antigenic peptide design, synthesis of long and/or modified peptides, MALDI TOF analysis, contract research, consultation services and more.
Biomedical researchers worldwide in universities, biotech companies, private clinics, and government agencies use products from Bio-Synthesis, Inc. in studies ranging from PCR diagnostics to cancer research and the Human Genome Project. Contact us to discover how BSI can customize products/services to suit your research requirements.
For more detail please visit our About Us
Please Contact Us :
Address: 612 E. Main street
City: Lewisville
State: Texas
Country: USA
Postal Code: 75057
Phone Number: 972-420-8505
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BIO-SYNTHESIS
BIO-SYNTHESIS, INC., is a leading life science products company with over 20 years of experience in the design and synthesis of Custom Peptide, small molecules and reagents for small scale research and bulk pharmaceutical trials. Using state of the art technology in our well-equipped laboratories.
Please visit our Blog on Blogspot Bio-Synthesis
Please visit our Blog on Blogspot Bio-Synthesis
Custom Peptides
As a leading supplier of genomic and proteomic research products, BSI is able to offer its customers integrated solutions for custom DNA synthesis, custom RNA synthesis, custom polyclonal antibody production, custom peptide synthesis, molecular diagnostic detection kits, DNA Real-Time PCR products, DNA microarray services and a wide range of custom DNA-based diagnostic kits and consumables.
The proteomic division is experienced in the design of peptides, both for antibody production and bioactive peptide synthesis, e.g cosmetic peptides. While the custom peptide synthesis division has the ability to produce thousands of modified or non-modified peptides per day for research applications, BSI also provides diagnostic/therapeutic GMP custom peptide production. Synthesis of custom peptides results in quantities ranging from milligrams to multi-kilograms. The staff in the custom antibody division provide expert support in the selection of peptide antigens for target antibody production and offer convenient custom-bundled packages with a wide range of host animals. In addition, peptide, antibody and protein arrays are also amongst its expertise.
BSI is a U.S. based company whose primary emphasis is on the synthesis of high quality custom products for a variety of applications and a full-service contract manufacturing organization (CMO) delivering research, development and production services for cGMP clinical batch manufacturing.
BIO-SYNTHESIS
BIO-SYNTHESIS, INC., is a leading life science products company with over 20 years of experience in the design and synthesis of Custom Peptide, small molecules and reagents for small scale research and bulk pharmaceutical trials. Using state of the art technology in our well-equipped laboratories.
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