Genomic Pioneers Gateway

Introducing an interview series with innovators, technologists and change makers in the genomics space called 'On the trail with Genomic Pioneers'.

On the Trail of Genomic Pioneers features cutting-edge research insights in genomics and brings forth the trend setting perspectives and inputs from the best in genomics research domain. Through this initiative, we try to bring the latest advancements and developments in the field of genomics.

Meet Prof. James R. Lupski,
Department of Molecular and Human Genetics
Baylor College of Medicine

The inaugural edition of our 'On the Trail of Genomic Pioneers' interview series features Prof. James R. Lupski, Department of Molecular and Human Genetics, Baylor College of Medicine. His research focuses on using human genetics, genomics, and molecular biological techniques to elucidate biological mechanisms for diseases. This interview gives fascinating insights into genomic disorders and discusses his research in this area.

To Read Dr. Lupski's Interview
Click here ...

Note : Lots More interviews of Researchers, webinars, and conferences are coming up ....

join the Genomic pioneeers gateway ...............

Topic: Biomarker qualification strategies in CNS disease

This webinar demonstrates how researchers can strengthen the qualification of a biomarker panel through the application of genomic reference data. Examples will be drawn from Gene Logic's research into CNS diseases such as Major Depression and Alzheimer's disease. These examples will include: (1) dysregulated genes that are related to aging rather than disease; (2) trace a dysregulated gene(s) from post-mortem brain tissue to peripheral blood and (3) determine whether the gene changes are disease specific.

Speaker: Jarlath ffrench-Mullen, PhD, Scientific Director, Gene Logic

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This webinar discusses biomarker identification of tissue injury using transcriptional profiles in blood cells. As background, examples from the literature will be presented including a case identified using some of the data in Gene Logic's reference database. To demonstrate how biomarkers that are unique and/or shared by diseases might be discovered, studies from Gene Logic's reference database will be used. The focus will be on white blood cells isolated from patients with autoimmune diseases including systemic lupus erythematosus, Wegener's granulomatosis and Crohn's disease.

Speaker:Donna Mendrick, PhD, VP Pharmacogenomics, Gene Logic.

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Nobody knows the value of patience more than those involved in Genomic Research. The painstaking efforts in research are transformed into tremendous success with perseverance and time. Sometimes the results may transform the very face of research. It is such transformational efforts that we wish to recognize through an exciting new award, Genomic Pioneers Award. The purpose of the Genomic Pioneers Award is to recognize excellence and outstanding contribution to the field of Genomics using integrated state-of-the-art approaches. The Award is funded by Ocimum Biosolutions. As Albert Szent-Gyorgyi a US biochemist said, "A discovery is said to be an accident meeting a prepared mind".

The first edition of the Genomic Pioneers Award focuses on the excellence in using Oligonucleotides in advancing Genomic Research. Synthetic DNA Oligonucleotides now have wide spectrum of applications ranging from being used in fundamental research, as diagnostic reagents to discovery of pharmaceutical compounds. This makes it an integral part of any scientific research. The Award will be conferred to a practicing scientist who has demonstrated excellence through their novel use of Oligonucleotides in Functional Genomics. There are 3 Awards being constituted each one in the months of September 2008, November 2008 and January 2009.

The winners of the maiden edition of the Genomic Pioneer Awards were announced at the HUGO's 13th international meeting on the Human Genome on 30 September, 2008.

The Genomic Pioneers Award winners are:

Europe: Dr. Sylvie Chauvaux, Asst Professor, Institut Pasteur, Paris.

Asia-Pacific: Dr. Juergen Pipper, Senior Scientist, Institute of Bioengineering and Nanotechnolog, Singapore.

India: Dr. Srikanta Kumar Rath, Scientist, Genotoxicity Laboratory, Central Drug Research Institute.

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Announcing the winners Anu Acharya, CEO, Ocimum Biosolutions, congratulated all the award winners on their achievement and hoped that this would motivate many others to participate in the upcoming editions of Genomic Pioneer Awards in subsequent years.

For instance, BNP is a potential biomarker for heart failure as this gene shows a high expression intensity in left atrium and ventricle.

We recently completed a biomarker discovery related work on cancer and have come up with a Discovery Wheel. This Discovery Wheel has leveraged our end-to-end capabilities, starting from data generation using Affymetrix and Agilent microarray platforms; analysis using our proprietary software tools; and validation using one of the world's largest biomarker reference database systems.

The Cancer Discovery Wheel shows how ASCENTA® System and services of Gene Logic can help at all stages of the cancer metastasis. Complete information on genes, their differential expression across various tissues, gene regulation across sample sets, and up and down regulation information are provided by ASCENTA® System.

ASCENTA®System provides a wealth of information such as:

Causative gene responsible for gene mutation
Chromosomal interactions to genes which are differentially expressed
Biomarkers responsible for angiogenesis
Biomarkers responsible for completing pathways responsible for metastasis

We invite you to work with us to identify your potential biomarkers of interest in your research. Please register yourself to work on ASCENTA® and to know more about our services capabilities.

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Overview

Gene Logic is a leading integrated genomics company providing comprehensive Genomic Reference Databases and GLP compliant Microarray Services. Over 2/3rd of the top 25 Pharma companies, leading research institutes and emerging biotech companies worldwide have chosen us as their preferred genomics partner and utilize our expertise for understanding underlying mechanisms of diseases, discovery and prioritization of gene targets & biomarkers. more ..

World's Largest Commercial Microarray Laboratory

*Global service provider
*Over 15 Years experience
*Over 300,000 samples processed
*Over 200,000 arrays processed
*Over 200 tissue types successfully handled
*Leader in the microarray space- over 60 applied patents
*High-throughput capacity
*Extensive quality control
*More than 30 quality control metrics employed
*Fast turnaround
*Data used as reference standard by FDA
*Study design using BioExpress® data

Quality

-> GLP Compliance for sample handling, RNA and DNA isolation, qRT PCR, Affymetrix and Agilent microarray services for gene expression
-> FDA uses our data has reference standard
-> Validated protocol
-> Multiple plateforms
-> Extensive QC Metrics

For more information download,