Ja Rule appeared with 0-1 and Chris Black as part of Cash Money Click (not to be confused with Cash Money Records). In 1998, Ja Rule was signed to Def Jam Recordings, with his first major appearance alongside Jay-Z on the song "Can I Get A...". In 1999, Ja Rule released his solo debut, Venni Vetti Vecci, and had a hit single "Holla Holla". The album went on to be a platinum hit and achieved multi-platinum success worldwide.

During early 2000 Ja Rule was also Featured on Irv Gotti's successful album, "Irv Gotti Presents... The Murderers". This album featured other Murder Inc. record label artists as well as DMX, Jay-Z and Busta Rhymes. In 2000 Ja Rule released Rule 3:36, his second album. The last single, "I Cry" featured Lil Mo. The album received an unexpected level of support, and went on to become 4x platinum.

On October 2 2001, Ja Rule released his third album, Pain Is Love. The first single, "Livin' It Up" was a hit which featured guest vocals by R&B singer Case and sampled Stevie Wonder's "Do I Do". The follow up single, "Always On Time", was released in December of the same year and was yet another mega success for the rapper. The song was notable as it introduced the public to singer Ashanti, who performed on the songs chorus. The album also featured the successful remix "I'm Real" with Jennifer Lopez. Finally, the album included the song "So Much Pain".

Ja Rule fourth studio album The Last Temptation was released on November 19 2002. Although the album was fairly successful (it was certified double platinum), it failed to carry the momentum brought by Rule's previous album. Lead singles, "Thug Lovin" (featuring Bobby Brown) and "Mesmerize" (featuring Ashanti) were successful.

During 2002 Ja Rule also featured on "Irv Gotti Presents... The Inc" and "Irv Gotti Presents the... Remixes" both albums were successful spawning such hits as "Down 4 U" and "Ain't It Funny Remix"

Blood In My Eye was Ja Rule's fifth album and was known for the weak tracks which were aimed at rapper 50 Cent, Eminem, Dr. Dre, Busta Rhymes, Diddy, Snoop, and others. It was certified gold in the U.S., a relative disappointment compared to his previous record sales.

Ja Rule released "R.U.L.E." On November 9 2004, and had hits with "Wonderful" (featuring R. Kelly), "New York" (featuring Fat Joe and Jadakiss), and "Caught Up" (featuring Alexi & Lloyd). The Ja Rule album was certified Platinum in the U.S and has gone on to sell 2.4 million copies worldwide making R.U.L.E. a successful return to the music industry after his feud with various other rap artists.

In fall 2005, Ja Rule released his Greatest Hits album, Exodus which included three new songs. Although the album didn't garner massive sales, it was put together just so Ja could fulfill his 7 album commitment to Universal and Def Jam Records. The Sub-Label Murder Inc, in which Irv Gotti and Ja Rule founded collapsed soon after. Ja Rule stepped down as an artist of Def Jam in a mutual agreement late 2005. It is rumored though that Ja Rule could be back at Universal under the Universal/Motown imprint of the label.

Ja Rule recently released new tracks from his upcoming mixtape M.I.3 on his myspace page, the mixtape features contributions from other artists such as Ashanti, Lil' Wayne, Nas, Black Child, Caddillac Tah and 0-1 and brand new signees Harry O, Young Life and The Gift. Ja Rule also is releasing his first single from his upcoming album Love Is Pain titled "Get Up".

Ja Rule appeared on the remix of "Rakata" by Wisin Y Yandel.

Even before signing with Interscope, 50 Cent was engaged in a well-publicized dispute with rival rapper Ja Rule and his label Murder Inc. Records. The rappers engaged in numerous mix tape "disses". The conflict stemmed from the rapper's friend allegedly stealing some of Ja Rule's jewelry, which led to a confrontation and 50 Cent's stabbing.

On 50 Cent's album, Get Rich or Die Tryin, 50 Cent hurled verbal shots towards Ja Rule and many other artists affiliated with Murder Inc., even mentioning Ja Rule's wife and children. Towards the end of 2003, Ja Rule dropped his album Blood In My Eye, which was almost exclusively dedicated to firing back to the "disses" that he received earlier (Clap Back and The Crown became successful hits). The battle between G-Unit and Murder Inc. continued on the mixtape level till Ja Rule's release of a song named "Loose Change", that targeted 50 Cent and G-Unit, and also mentioned Eminem's daughter and claims that "Dr.Dre is a bisexual." Busta Rhymes, 50 Cent, and Eminem responded by releasing the remix track of 2pac's classic "Hail Mary." Dr. Dre responded by appearing on Obie Trice's "Shit Hits the Fan" along with Eminem. Dre rapped about how Ja Rule wasn't on his level, how Ja Rule is nothing like Pac, and to stop acting hard for Ja Rule looks like an asshole. Ja Rule consequently released the remake of "Who Shot Ya". The feud appeared to die down until in early 2006, when Ja Rule along with other Murder Inc. artists released "diss" tracks "21 Gunz" and "So Hot".

Eminem became involved with Ja Rule for several reasons: over Ja Rule's involvement with The Source (a popular hip-hop magazine), with Eminem's involvement with 50 Cent, and with Ja Rule's mention of Eminem's daughter Hailie in the track "Loose Change" (On the track, Ja Rule raps "Em, you claim your mother's a crackhead, and Kim is a known slut, so what's Hailie going to be when she grows up?"). Numerous "diss" tracks were traded back and forth by both rappers such as a remix of Tupac's hit song, Hail Mary, which featured 50 Cent and Busta Rhymes.

Ja Rule, Irv Gotti, and other Murder Inc members immediately sided with Benzino since they shared a common beef.

It does appear, however, that the feud has ended with both rappers claiming that they want no more problems. Eminem has discussed his feelings concerning the feud with his single, "Like Toy Soldiers."

But Eminem did annihilate Ja Rule, the song Bump Heads clearly end Jeffrey Atkins' career, fortunately for everyone.

The beef from Game towards Ja Rule is due to business affiliation since The Game was working for 50 Cent's G-Unit. After The Game was kicked out of G-Unit by frontman 50 Cent, The Game released a single called "It's Okay (One Blood)", which features a remix over 11 minutes long with over 20 of rap's most elite MCs. Although The Game was heavily involved with G-Unit's beef with Ja Rule, the two have since squashed their beef and Ja Rule commits 16 bars on the remix. There was a poll on allhiphop, which asked who's verse was the best, Ja Rule's verse was voted the best. The two MCs have also collaborated on Ja Rule's new album on a track titled "Sunset".

Ja Rule has beefed with other artists such as DMX who claimed that Ja Rule has copied is rough voice. This beef was squashed in 2006 when a representative of Ja Rule visited DMX in prison. DMX originally wanted ot sorted out with fists, but the two rappers talked their way through.

Ja Rule has also beefed with Busta Rhymes after Ja Rule made coments about him in a magazine. Busta Rhymes appeared on a diss track with Eminem and 50 Cent called Hail Mary, which was a remix of 2Pac's original. In the song, 50 Cent brings forward the fact that Ja Rule is using 2Pac's style, and that 2Pac would also be beefing with Ja Rule if he could hear him today.

25 To Life
4 Seasons
6 Feet Underground
Ain't It Funny (Murder Remix)
Always On Time
Always On Time (Part 2)
Been Around the World
Between Me And You
Big Remo (Skit)
Bitch Betta Have My Money
Caught Up
Caught Up (Dirrty)
Clap Back
Clap Back ( Video Verson)
Connected
Count On Your Nigga
Daddy's Little Baby
Damn (Should've Treated U Right)
Dem Niggaz
Destiny
Dial M For Murder
Die
Down Ass Bitch
Down For U 12' (Down Ass Bitch Remix)
Down For You
E-Dub & Ja
Emerica
Extasy
F*** You Feat. Vita
First Degree
Fuck You
Furious
Furious (Feat. Vita And 01)
Furious (feat. O1, Vita)
Get Away
Grand Finaly
Holla Holla
Holla Holla (Remix)
How Many Wanna Die
How Many Wanna(Dirty)-Light It Up Soundtrack
I Cry
I'm Real (Murder Remix)
It's Murda
It's Your Life
It's Your Life
Kill 'Em All
Last Temptation
Late Nites
Leaving
Leo
Lets Ride
Life Ain't A Game
Live My Life
Livin' It Up
Loose Change
Loose Change (50, Shady Aftermath, Dre Diss)
Lost Little Girl
Love Me, Hate Me
Mesmerize
Mezmerize (Radio Version)
Mezmerized Feat. Ashanti
Murda 4 Life
Murder Me
Murder Reigns
Murderers
Never Again
Niggaz Theme
One Of Us
Only Begotten Son
Pain Is Love
Pain Is Love (Skit)
Pop Niggas
Put It On Me
Put It On Me (Ft. Vita & Lil Mo)
Race Against Time
Rainy Dayz
Rebels Symphony
Reign
Reign, The
Represent
Rock Star
Shit Gets Ugly
Smokin And Ridin
So Much Pain
Story To Tell
Suicide Freestyle
Survival Of The Illest (Intro)
Survival Of The Illest 2 Intro
The Crown
The Inc.
The March Prelude
The Murderers
The Only Begotten Son
The Pledge
The Pledge (Remix)
The Rain
The Reign
The Rule Won't Die
The Warning
Thug Life
Thug Lovin'
Trick
True Love
Watching Me (Rule 3:36)
We Did It Again
We Did It Again (Feat. Metallica)
We Different
We Here Now
Where Would I Be (Feat. Vita)
Wonderful feat R Kelly and Ashanti
World's Most Dangerous
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