Fat cells in all mammals produce the powerful, newly discovered hormone called which turns out to be a principal force in the body for managing and balancing balance including pancreatic thyroid leptin research has given us insight into its' effects leptin is:

• Responsible for controlling appetite and fat storage


• Responsible for telling the liver what to do with its stored glucose

In addition to these actions, leptin also acts directly on:

• the cells of the liver and skeletal muscle where it stimulates the oxidation of fatty acids in the mitochondria. This reduces the storage of fat in those tissues (but not in adipose tissue (fat).


• T cells where it enhances the production of Th1 cells promoting inflammation. People with obesity, or who are overweight with leptin resistance, also have super high levels of leptin, leading to cellular inflammation in its many forms

Leptin communicates directly with your brain, telling the brain when you are full and do not need more food, when you are empty and need to eat to replenish your energy and what to do with fat: store it or burn it. It controls your appetite, energy, and metabolic rate and is the primary reason for food cravings, overeating, faulty metabolism, obsessions with food and heart disease.

Leptin is sent by the fat cells to the brain where it is meant to tell the brain that you are full and do not need more food and after a while your fat cells get smaller again and as they do this they produce less leptin. Lower leptin levels signal your brain to fill up the fat cells again and you become hungry and eat. You eat, and that fat cells fill up, they send out more leptin and the brain shuts off your hunger again and so on and on this goes.

Well that how it is supposed to work. Unfortunately this appetite cycle has become confused and we can see the results in the obesity epidemic that is sweeping the world.

This hormone is a potential key to permanent weight loss for many, because the higher your leptin levels the thinner you are meant become. However as it is fat cells that create leptin and the more fat cells you have the more leptin you have, the question becomes, why are overweight people still overweight?

The original researchers thought that they had found the answer when they injected leptin deprived obese mice with leptin and they lost weight. So these researchers went about measuring the leptin levels humans of varying weights expecting obese humans to have low leptin levels.

To their surprise, it turned out the obese people invariably had high leptin levels, which was when it was suggested that this syndrome might be similar to insulin resistance where subjects have high levels of insulin yet their cells are resistant to its effects.

So while a few people, who had low leptin levels did respond to injections of leptin, the studies proved that obese people who had high levels of leptin did not respond to the injections at all.

The key to weight loss definitely lies with insulin and leptin and with reducing the cells resistance to them, not with increasing the levels of them which would allow the appetite cycle to work normally.

The chemical known to causes this cellular resistance is named Resistin, a worthy name for such a chemical. Resistin causes tissues (especially the liver), to be less sensitive to the action of insulin and over time leptin and there is a strong association between elevated levels of resistin; obesity and Type 2 Diabetes.

Dr Ron Rosedale, who wrote the book, "The Rosedale Diet" and has become one of the world's foremost researchers into leptin it's causes and cures has some suggestions. First of all daily exercise and the reduction in eating all refined and processed foods such as white bread, pasta, cookies, sugar based foods, in fact all high GI foods. He also suggests maintaining a five hour gap between all meals to allow time for your fat cells to shrink.

Dr Rosedale has also become interested in the research into a newly developed product called Leptivin, which seems to be giving unbelievable results for many who have trialled it. Double blind studies are continuing and the results are looking good. Leptivin is the main ingredient in a new formula called MaxWLX which is proving to be a breakthrough for so many people.

MaxWLX has been tested in a controlled clinical study by the University of Connecticut. Participants in this double-blind study lost an average of:

• 21.5 pounds of Body Fat in 8-weeks.


• 3.96 inches off their waists.


• 3.28 inches lost from their hips.


• 1.20 inches off each thigh.

Leptin may have yet more influence within our bodies and studies are continuing into the many facets of leptins influence and some researchers are concluding that it also influences: diabetes, triglyceride levels, body weight, metabolism and reproductive function just for a start.

Lose Weight fast with MaxWLX by controlling Leptin. Lose excess fat and keep lean muscle.