A Primer on Antioxidants and Free Radicals

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Oxygen - Friend and Foe

We can survive without food or water for several days but a few minutes without oxygen can kill us. Oxygen is very important for our existence. On the other hand, it can also slowly destroy our body. Let's find out why. 

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Antioxidants and Free Radicals 

Oxidation is a natural occurrence. It happens when some atoms or molecules reacts with oxygen. Oxygen is like a magnet for electrons. Molecules whose electrons are not tightly bonded to its nucleus tends to give up an electron to the oxygen. That molecule is then said to be oxidized.

Most stable atoms and molecules have electrons that are in pairs. If one of the electrons loses its pair(becomes a free radical), their tendency is to 'steal' an electron from neighboring atoms to make itself 'whole' so to speak. This becomes the onset of a free radical chain reaction until an antioxidant is encountered.

We witness oxidation in our everyday lives: iron rusts when exposed to oxygen, meat of fruits turn brown when exposed to oxygen, meat fat getting rancid when exposed to oxygen.

Oxygen when combined with some molecules seems to be very destructive, isn't it?

Oxidation does not only happen outside our bodies.

We breathe oxygen and our blood distributes it to our cells giving us life and at the same time exposing our insides to possible free radical chain reactions.

The mitochondria, the energy producer of a cell, requires oxygen to manufacture energy. The process undergoes several controlled oxidation of several molecules until energy(ATP) is produced. A by-product of this process are free radicals. Heavy physical activities can multiply these by-product of free radicals several times because of the cells need to produce more energy.
The more energy is produced, the more free radicals escape the production process.

Free radical chain reactions can damage or 'deform' healthy cells. The onset of many degenerative diseases may be caused by these damages that free radicals leave behind. Some diseases that may be caused by free radicals are Alzheimer's disease, cardiovascular disease, macular degeneration and even cancer.

Researchers has also discovered that cell damages caused by free radicals are one of the factors that causes aging. Minimizing free radical chain reactions can increase our average life span.

 

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You Could Look Younger At Your Age 

Let's try a little thought experiment. Supposing a man named John Doe who is particular in taking antioxidants whether from food or from supplements and man named Mr. X who doesn't care on taking antioxidants. Let's also assume that they are living in the same conditions and in the same place. Assuming that the average life span of a person in their situation is 70 and taking antioxidants would increase their life span to 80.

The middle age of John Doe would then be 40 and Mr. X would be 35. If both men were at the age of 35, John Doe would then be looking younger and stronger than Mr. X because he still has not reached his middle age. So it may be said that John Doe is 5 years younger than Mr. X even though their chronological age is the same.

Perhaps this could be one reason why you sometimes hear people say: 'Elizabeth looks younger at her age'

Let's just leave it at that, a thought experiment. No one may not be able to prove that.

Since oxidation is a natural occurrence, our bodies are also equipped with 'defenses' for that.

 

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Antioxidants to the Rescue 

Antioxidants are molecules that can give up or donate an electron to another molecule without becoming unstable or reactive. When a free radical 'steals' an electron from an antioxidant, the chain reaction stops.

Our bodies have internal antioxidants on 'stand by' to stop free radical reactions. Some of these are:
Superoxide Dismutase(SOD)
Glutathione
CoQ10

But sad to say, some internal antioxidants are produced less by our bodies as we age especially when we reach about the age of 30 like glutathione and CoQ10.

Glutathione levels can be raised by supplementing with N-Acetyl Cysteine. N-Acetyl Cysteine not only raises glutathione levels but has other properties that are really beneficial to our bodies.

CoQ10 is also better supplemented as we age. Like N-Acetyl Cysteine, it is not only a potent antioxidant but it also has other properties that benefits our bodies.

Assisting these 'internal' antioxidants, we also take in 'external' antioxidants from the food we eat like:
Vitamin C
Vitamine E
Beta Carotene(Vitamin A)
Bioflavonoids from fruits and vegetables

The food we eat may not be enough to supplement our antioxidant requirements mainly because of our eating habits. It would take quite a discipline to stick to a diet to meet our antioxidant needs.

There are also external causes that can build up free radical reactions in our body like smoking, toxic fumes, second hand smoke from smokers and radiation from sunlight. Even irregular exercise can cause free radical chain reactions.

The need for supplements may be the answer to keep up with our antioxidant requirements especially when we reach 30 years old.

Funny how oxygen can be life giving and at the same time life threatening. But this is the world we live in - everything has an opposite; male-female, light-dark, cold-hot, peace-war. What matters is how we deal with it.

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Do you think antioxidants are important? 

Did you find this information useful? I'd appreciate comments.

SemperFidelis wrote...

Antioxidants are key to cancer prevention.
Blessed by a Squid Angel today! :)
Colleen ~ www.squidoo.com/squid-angel

ReplyPosted August 13, 2008

Lensmaster

Yap! I do agree with you that oxygen today can kill because of toxins and free radicals! But you can't avoid them, right? The best thing is to find a way to detoxify ourselves and the things you have presented here can sure be a big help in maintaining good clean living! thanks for sharing! and by the way, if you have the time, do drop by this site that offers different kinds check registers ! have a nice day and thank you!

ReplyPosted August 04, 2008

Christopher_Scott wrote...

Gotta love those antioxidants!

ReplyPosted February 03, 2008

lprince wrote...

Great Lens,
I am giving you 5 stars. I'm taking GoChi which is also a great antioxidant.

ReplyPosted January 30, 2008

flowergardener wrote...

Great Lens! Welcome to the Vitamin Supplements Group.

ReplyPosted September 26, 2007

 
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Antioxidants in Food 

Obtain antioxidants from the food you eat.

Xanthones - 40 out of 200 known varieties of xanthones can be found in the
mangosteen
. These are powerful antioxidants and the highest concentration in mangosteen can be found in the pericarp.

Anthocyanins - Plant pigments that can be found in dark colored fruits. These antioxidants provide protection from the fruits and is most concentrated in the skin or peel areas.
Acai berries
and blueberries has high amounts of anthocyanins.

Punicalagin - This is the major antioxidant component of
pomegranate
.

EGCG (Epigallocatechin gallate) - These are potent antioxidants found in tea. Green
tea
has the highest concentrations of egcg among the tea varieties. Black tea and Oolong tea has fewer concentrations of these antioxidants.

Generally, the darker the fruit the higher its antioxidant potency. Fruits and vegetables have a lot of natural antioxidants so don't forget your daily intake of these nutritious and antioxidant filled food.