Peripheral Stem Cell Transplant

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My experience donating stem cells

This is my attempt to write an account of my recent experience donating stem cells for my brother. When I was first asked to be a donor, I scoured the web to learn about the procedure and I especially wanted to read first hand stories. There weren't many, so I have decided to pass on the following in the hope it will help others.

What are stem cells? 

Adult stem cells reside throughout the human body within tissue, blood and organs; they are plentiful and readily available. Adult stem cells refers to the stage or maturity of the stem cell. Adult stem cells are also found in the tissues of the umbilical cord (after live birth), spinal cord, fat, bone marrow, dental pulp, nasal cavity, brain, peripheral blood, blood vessels, skeletal muscle, skin, cornea, digestive system, retina, liver, and pancreas.

Nupagin shots 

Stimulation of stem cells

After it had been determined I was a perfect match for my brother, I had a physical and lots of blood work. I passed my tests and then it was on to phase one.
This involved 6 days of neupogin shots which stimulate the release of stem cells from the bone marrow into my blood so they can be harvested for my brother. It's important during this period to drink plenty of water. I had decided to go to the hospital each day for the shots, but some people opt to do it at home.

The shots sting a bit and after the first several days, mild bone aches began- mostly in my hip and sternum. It was nothing that an occasional tylenol couldn't remedy.

Apheresis 

Harvesting the stem cells

On the fifth day, I reported to the hospital at 7 am and was prepped for the apheresis or the removal of my stem cells. I was hooked up to a centrifuge machine: one line brought the blood out from an arm into the machine where the blood was separated and the stem cells were collected into a bag and my blood was returned to me in another arm.
An anticoagulant was going through my system to prevent clotting and calcium was also given.
Aside from the discomfort of being in bed and not really able to move around for 6 or 7 hours, it was not unpleasant.
Unfortunately, the first harvest did not capture enough stem cells for my brother- this is determined by patient weight, I believe- so I returned to the hospital the following morning to repeat the procedure.
I had been worried about side effects from the Nupagin as well as the apheresis, but the only side effect was several days of fatigue.

Prepare for your procedure 

Question, question, question

My advice to anyone contemplating a peripheral stem cell procedure is to learn as much as you can in advance. Ask questions of the doctors and nurses who are caring for your loved one and who are working with you. The procedure is much less painful than bone marrow aspiration. Most of us are squeamish when it comes to the subject of blood, but the more you understand what is going on, the less nervous you will be.
We are now in week three of the transplant and are in a watch and wait mode. My brother has been great through all of this- as have the staff at the hospital.

Latest update 

It has been approximately six months since the transplant and my brother is back at work. He continues with bi-monthly doctor visits. They are continuing to monitor his meds and occasional host versus graft episodes. He has made amazing progress!

Be a Donor 

Give the gift of life

National Marrow Donor Program
When you become a bone marrow donor, you join the global movement of more than 11 million donors who stand ready to give someone a future.

Great Stuff on Amazon 

Have you donated stem cells? 

Tell us about your experience.

Lensmaster

Beth wrote

Thank you for sharing your story. More poeple need to know how very simple it is to help another in this manner. It is such a wonderful feeling too ! Here is my story: After having major surgery, and 23 days in the hospital, my brother sent the word out that he needed stem cells. Luckily, we have 7 kids in our family. Guess what... I was the only one who matched. He lives in another state, so off I went to Chicago for my physical.. full torso brace and all. That all went great..returned a few weeks later to harvest. The only side affect I got was major headaches from the Nueopogen. He will receive my 'girlie blood' next week... and it tugs at my heart that I can't be there for him. This all is such an emotional ride for all of my big family..spread over 4 states. I wish all of your stem cell recipients well for years and years! Good luck Mark, my heart is with you!

Reply Posted May 01, 2009

babythymes wrote...

Thanks for sharing your experience- how wonderful for you and your sibling. It is a joyful and awe-inspiring adventure- Best regards

ReplyPosted February 19, 2009

Lensmaster

susan wrote

when first asked i jumped at the chance both my younger sister & i were tested. it turned out i was a perfect 10 (the first in my life) i was apprehensive about the procedure so i read all i could. as my sister & i live in different states i went to the state of ga. were the precedure was to be done for my phycical.After passing that it consisted of many viles of blood questions lots of the & a chest exray. i was shown how the machine worked and that was it. i returned a few week later for the collection. i was given shots to stimulate stem cell growth for 5 days then it was time for collection. it lasted 4 hrs. at the end of the day i had a terrible headache then it was over. the most gratifying thing was being there when she received them. people say i gave her a gift but she was the one who gave me the gift. it has been 23 day the engraphment is taking & there is no greater joy than knowing we were both part of something. wonderful.

Reply Posted February 18, 2009

by babythymes

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