Stemulite - Controversial New Supplement

Accelerated muscle building has long been the goal of physical trainers and trainees. Myriad training programs, diets, and combinations of regimens litter the landscape of health and fitness publications.

Millions of disappointed participants, millions of wasted dollars and tons of "meal replacements", protein, creatine, amino acids, and peptide supplements have produced little or no lasting effect to the users.

With the discovery of the adult stem cell found in the bone marrow of adults by Catherine Verfaillie at the University of Minnesota in 2002 it became obvious that stem cells carried an enormous potential to accelerate and enhance the building of new muscle and other tissues in the human body.

John Cooke, et al., of Stanford University later identified a specific agonist and receptor for adult stem cells and demonstrated a mechanism of action for the de novo building of blood vessels in blood-starved limbs of animals.

It followed that not only blood vessels but any tissue theoretically could be built or be remolded with adult stem cells.

Two new types of stem cells have been found that can seek out injured muscle tissue and replace the damage cells.

The stem cells then multiply and form new muscle fibers, replacing the injured tissue.

Body builders heretofore have mainly concentrated on ingesting enormous amounts of proteins and amino acids in order to replace protein stores in workout muscles.

This is good to a point.

The point is that the body is grossly overloaded with high protein supplements that can in continued unabatedly, lead to various disease and organ dysfunction.

A method that does not require or can considerably reduce such metabolic overload would be highly desirable and would obviously find a huge market.

Obviously such protein overload does little for the injured tissue accompanying intense workout.

And the sometimes agonizing pace of muscle accumulation leads most to drop out in disappointment.

This theme recurs in other tissues as well. For example, bone marrow stem cells can home in on and repair damaged heart and pancreas tissue.

The research could lead to new treatments for muscle-wasting diseases, such as muscular dystrophy, and for restoring muscle strength in elderly people.

Stem Cells Seek Out Growth Factors
The studies reveal how different types of stem cells repair injured muscle and point to common: Damaged tissue sends out molecular signals that attract new stem cells.

The stem cells then multiply and form new muscle fibers, replacing and repairing injured tissue.

Until now the signals that recruit stem cells to sites of injury have been unknown.

Understanding these signals may be key to finding new ways to replace damaged tissues by encouraging the growth of stem cells already in the body.

Researchers found that stem cells from normal tissue would not multiply in culture, but those isolated from injured muscle readily proliferated and gave rise to new muscle cells.

The researches also found that a protein release from injured muscle, called Wnt, stimulates the stem cells to form new muscle cells.

Wnt also signals new muscle tissue form in the developing embryo.

As people age, these signals diminish and cells lose their ability to regenerate.

But understanding the signals that trigger muscle regeneration could lead to new strategies for increasing muscle strength in both aging and diseased tissues.

For example, Wnt has been shown recently to stimulate the growth of adult bone marrow stem cells.

Growth factors such as fibroblast growth factor (FGF) and hypoxic inducible factor (HIF) are involved in tissue repair and growth.

When exercise is intense and carried out to fatigue, oxygen is depleted from the muscle and HIF is released.

It is thought that HIF and Wnt work together to recruit somnambulant bone marrow stem cells to mobilize and migrate to the hypoxic zone.

Cooke demonstrated that progenitor stem cells are attracted to the release of acetylcholine by binding of acetylcholine receptor agonist (AChR-A), especially the nicotinic receptor.

Metabolic Research scientists have combined a natural botanical extract derived from the edible eggplant containing this agonist in its natural form into to dietary supplement.

The supplement also contains a rare earth mineral called Indium. Recently Indium has been found to greatly enhance strength and endurance.

Indium is not quite a household word, yet I believe it will be on every "strength jock's" must-have list in the very near future.

While indium has been used for years in medicine (it is used in diagnostic imaging) and has FDA approval for its use, (it would take 20,000 times more than its present use to become toxic) its use in nutritional supplements is new.

Within 5-10 days Indium begins producing lower body weight, in fact, it is thought to do this via stimulation of human growth hormone (hGH) which is known to replace body fat with muscle.

Indium potentiates thyroid gland output which provides higher metabolism improves mood, and increased tolerance for activity while reversing age-related weight gain.

With in 5 -10 days, the strenuous exerciser, who normally stops exercising due to muscular pain, should be able to increase repetitions by 10%.

In one study of 15 male Kung Fu practitioners taking 5 mg of indium per day demonstrated a 20% increase in stamina and endurance at 60 days use.

In one study of distance runners, after two weeks of indium supple at the same dose, demonstrated a 30% increase in endurance.

These two compounds are conjugated on the a beta glucan molecule and comprise the basic ingredient of the muscle mass accelerator, Stemulite%u2122.

We can easily add additional proteins and other dietary supplements to make other products based on the original equal to any of the current high-protein products.

None of the current competition has the two highly effective and non steroidal effects that we will have.

Metabolic Research is beginning to supply this compound to Personal Trainers via is network of Exercise Fitness Advisors such as Stephen Holt.