Vitamin D Deficiency
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Vitamin D: Antidote to Winter and the Darkness
The scientific literature shows that millions of Americans are deficient in vitamin D. Vitamin D isn't patentable. No one sends out drug reps to sell it to your doctor. So the vitamin d deficiency that you likely have is probably undiagnosed!
Vitamin D: Antidote to Winter and the Darkness
Winter Blahs? General Malaise? Read this book!
I had the pleasure of sitting next to Dr. Merrill at the Buffalo Book Fair. He is passionate about two things, Vitamin D and helping people improve the quality of their lives. This book tells his story and so much more. The general gist lies within the fact that diminished sun exposure with the accompanying lack of Vitamin D, adversely affects many organs in our bodies, thereby causing a wide range of malfunctioning systems found in such problems as mood and auto-immune disorders, cancers, muscle and bone weakness and generalized pain. In his book, Dr. Merrill presents a comprehensive argument for the inherent value of Vitamin D therapy. For those receptive to a holistic, preventative approach to health, this book will "light" the way. - Linda A. Lavid (Buffalo, NY United States)
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Vitamin D Deficiency
Vitamin D is a group of fat-soluble prohormones, the two major forms of which are vitamin D2 (or ergocalciferol) and vitamin D3 (or cholecalciferol). Vitamin D obtained from sun exposure, food, and supplements, is biologically inert and must undergo two hydroxylation reactions to be activated in the body. Calcitriol (1,25-Dihydroxycholecalciferol) is the active form of vitamin D found in the body. The term vitamin D also refers to these metabolites and other analogues of these substances.
Category: File - :Calcium regulation.png|thumb|250px|Calcium regulation in the human body.Page 1094 (The Parathyroid Glands and Vitamin D) in: The role of vitamin D is shown in orange.
Calcitriol plays an important role in the maintenance of several organ systems. However, its major role is to increase the flow of calcium into the bloodstream, by promoting absorption of calcium and phosphorus from food in the intestines, and reabsorption of calcium in the kidneys; enabling normal mineralization of bone and preventing hypocalcemic tetany. It is also necessary for bone growth and bone remodeling by osteoblasts and osteoclasts.
Without sufficient vitamin D, bones can become thin, brittle, or misshapen. Deficiency can arise from inadequate intake coupled with inadequate sunlight exposure; disorders that limit its absorption; conditions that impair conversion of vitamin D into active metabolites, such as liver or kidney disorders; or, rarely, by a number of hereditary disorders. Vitamin D deficiency results in impaired bone mineralization and leads to bone softening diseases, rickets in children and osteomalacia in adults, and possibly contributes to osteoporosis.
Vitamin D plays a number of other roles in human health including inhibition of calcitonin release from the thyroid gland. Calcitonin acts directly on osteoclasts, resulting in inhibition of bone resorption and cartilage degradation. Vitamin D can also inhibit parathyroid hormone secretion from the parathyroid gland, modulate neuromuscular and immune function and reduce inflammation.
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