Tuscany (Italian: Toscana) is one of the twenty Regions of Italy. The capital is Florence, and it has an area of 22,990 km² and about 3.6 million inhabitants. Tuscany is known for its landscapes and its artistic legacy. Six Tuscan localities have been made UNESCO protected sites: the historical center of Florence (1982), the historical center of Siena (1995), the square of the Cathedral of Pisa (1987), the historical center of San Gimignano (1990), the historical center of Pienza (1996) and the Val d'Orcia (2004).

The main attractions of Tuscany are:
* Siena (by train, 1.5 to 2 hours)
* Pisa (by train, 1 to 1.5 hours)
* San Gimignano (by train to Poggibonsi, 1 hour ride, and then a bus that runs every 30-40 minutes, 25 minute ride)
* Volterra (also reachable by bus from Poggibonsi)
* Pienza (reachable by bus from Siena, a little more than an hour, but connections are not frequent)
* Lucca (by train)
* Arezzo

Campania is a region of Southern Italy, bordering on Latium to the north-west, Abruzzo and Molise to the north, Apulia to the north-east, Basilicata to the east, and the Tyrrhenian Sea to the west. The region covers 13,595 km² and has a population of 5.8 million.

The name derives from Latin, as it was called by Romans Campania felix ("fortunate countryside"), a name that is shared by the French province of Champagne.

Tourist attractions include the Sibyl's cave at Cumae, the Greek temples at Paestum, the Roman ruins at Pompeii and Herculaneum, the volcanoes of Vesuvius, Campi Flegrei, the Amalfi Coast (Costiera Amalfitana) , the Sorrento Peninsula (Penisola Sorrentina) and the islands of Capri, Ischia and Procida.

Umbria is one of the 20 Regions of Italy. The capital is Perugia. It has an area of 8,456 km² and about 900,000 inhabitants.

Major cities are:

* Perugia - the capital
* Assisi
* Gubbio
* Montefalco
* Orvieto
* Otricoli
* Spello
* Spoleto
* Terni
* Todi

Lazio (Latium in Latin) is a regione of central Italy, bordered by Tuscany, Umbria, Abruzzi, Marche, Molise, Campania and the Tyrrhenian Sea. Lazio is notable for its history, art, architecture, archaeology, religion and culture.

The best destinations are:
* Frosinone
* Fiumicino
* Gaeta
* Rieti
* Rome
* Rome-Lido di Ostia
* Ostia Antica
* Sperlonga
* Tivoli
* Viterbo
* Civita di Bagnoregio
* Civitavecchia

Apulia (Italian: Puglia ['pu%u028E%u02D0a]) is a region in southeastern Italy bordering the Adriatic Sea in the east, the Ionian Sea to the southeast, and the Strait of Òtranto and Gulf of Taranto in the south. Its southern portion known as Salento, a peninsula, forms the heel of the Italian "boot". The region comprises 19,345 km² (7,469 square miles), and its population is about 4 million. It is bordered by the other Italian regions of Molise to the north, Campania to the west, and Basilicata to the southwest. It neighbors Greece and Albania, across the Ionian and Adriatic Seas, respectively. The region extends as far north as Monte Gargano, and was the scene of the last stages in the Second Punic War.

There are a lot of things to see in Puglia: Trulli in Alberobello, Old town in Bari, Trani, beaches in Monopoli.

You can also see the Castellana Grotte, Castel del Monte, the castle of Federick II, Polignano, Conversano, Martina Franca and Ostuni, the "white city".